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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Defects in mitochondrial metabolism and cancer
|
|---|---|
| Published in |
Cancer & Metabolism, July 2014
|
| DOI | 10.1186/2049-3002-2-10 |
| Pubmed ID | |
| Authors |
Edoardo Gaude, Christian Frezza |
| Abstract |
Cancer is a heterogeneous set of diseases characterized by different molecular and cellular features. Over the past decades, researchers have attempted to grasp the complexity of cancer by mapping the genetic aberrations associated with it. In these efforts, the contribution of mitochondria to the pathogenesis of cancer has tended to be neglected. However, more recently, a growing body of evidence suggests that mitochondria play a key role in cancer. In fact, dysfunctional mitochondria not only contribute to the metabolic reprogramming of cancer cells but they also modulate a plethora of cellular processes involved in tumorigenesis. In this review, we describe the link between mutations to mitochondrial enzymes and tumor formation. We also discuss the hypothesis that mutations to mitochondrial and nuclear DNA could cooperate to promote the survival of cancer cells in an evolving metabolic landscape. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 67% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 33% |
| Members of the public | 1 | 33% |
| Scientists | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 309 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 6 | 2% |
| United States | 4 | 1% |
| Greece | 1 | <1% |
| Italy | 1 | <1% |
| Unknown | 297 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 76 | 25% |
| Researcher | 54 | 17% |
| Student > Master | 35 | 11% |
| Student > Bachelor | 24 | 8% |
| Other | 15 | 5% |
| Other | 48 | 16% |
| Unknown | 57 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 86 | 28% |
| Biochemistry, Genetics and Molecular Biology | 80 | 26% |
| Medicine and Dentistry | 32 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 8 | 3% |
| Chemistry | 8 | 3% |
| Other | 21 | 7% |
| Unknown | 74 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 April 2024.
All research outputs
#7,017,640
of 25,637,545 outputs
Outputs from Cancer & Metabolism
#78
of 226 outputs
Outputs of similar age
#58,360
of 227,945 outputs
Outputs of similar age from Cancer & Metabolism
#3
of 6 outputs
Altmetric has tracked 25,637,545 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 226 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.2. This one has gotten more attention than average, scoring higher than 65% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 227,945 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.