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Increased blood–brain barrier permeability and alterations in perivascular astrocytes and pericytes induced by intracisternal glutaric acid

Overview of attention for article published in Fluids and Barriers of the CNS, July 2014
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Title
Increased blood–brain barrier permeability and alterations in perivascular astrocytes and pericytes induced by intracisternal glutaric acid
Published in
Fluids and Barriers of the CNS, July 2014
DOI 10.1186/2045-8118-11-15
Pubmed ID
Authors

Eugenia Isasi, Luis Barbeito, Silvia Olivera-Bravo

Abstract

Glutaric acid (GA) is a dicarboxylic acid that accumulates in millimolar concentrations in glutaric acidemia I (GA-I), an inherited neurometabolic childhood disease characterized by extensive neurodegeneration. Vascular dysfunction is a common and early pathological feature in GA-I, although the underlying mechanisms remain unknown. In the present study, we have used a previously-validated rat model of GA-I to determine the effect of GA on the blood- brain barrier (BBB) and the neurovascular unit.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 3%
Australia 1 3%
Unknown 36 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 24%
Student > Bachelor 6 16%
Student > Doctoral Student 4 11%
Student > Master 4 11%
Professor 4 11%
Other 8 21%
Unknown 3 8%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 29%
Neuroscience 7 18%
Medicine and Dentistry 6 16%
Biochemistry, Genetics and Molecular Biology 4 11%
Unspecified 2 5%
Other 4 11%
Unknown 4 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 December 2021.
All research outputs
#20,744,283
of 25,483,400 outputs
Outputs from Fluids and Barriers of the CNS
#375
of 500 outputs
Outputs of similar age
#175,677
of 240,170 outputs
Outputs of similar age from Fluids and Barriers of the CNS
#4
of 7 outputs
Altmetric has tracked 25,483,400 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 500 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 240,170 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.