↓ Skip to main content

Functional and genetic analysis of the colon cancer network

Overview of attention for article published in BMC Bioinformatics, May 2014
Altmetric Badge

Mentioned by

twitter
2 X users

Citations

dimensions_citation
35 Dimensions

Readers on

mendeley
46 Mendeley
citeulike
1 CiteULike
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Functional and genetic analysis of the colon cancer network
Published in
BMC Bioinformatics, May 2014
DOI 10.1186/1471-2105-15-s6-s6
Pubmed ID
Authors

Frank Emmert-Streib, Ricardo de Matos Simoes, Galina Glazko, Simon McDade, Benjamin Haibe-Kains, Andreas Holzinger, Matthias Dehmer, Frederick Charles Campbell

Abstract

Cancer is a complex disease that has proven to be difficult to understand on the single-gene level. For this reason a functional elucidation needs to take interactions among genes on a systems-level into account. In this study, we infer a colon cancer network from a large-scale gene expression data set by using the method BC3Net. We provide a structural and a functional analysis of this network and also connect its molecular interaction structure with the chromosomal locations of the genes enabling the definition of cis- and trans-interactions. Furthermore, we investigate the interaction of genes that can be found in close neighborhoods on the chromosomes to gain insight into regulatory mechanisms. To our knowledge this is the first study analyzing the genome-scale colon cancer network.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 2%
Bulgaria 1 2%
Austria 1 2%
Unknown 43 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 28%
Student > Ph. D. Student 8 17%
Student > Bachelor 4 9%
Professor > Associate Professor 4 9%
Student > Master 4 9%
Other 6 13%
Unknown 7 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 13 28%
Computer Science 10 22%
Medicine and Dentistry 3 7%
Biochemistry, Genetics and Molecular Biology 3 7%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Other 6 13%
Unknown 10 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 October 2014.
All research outputs
#17,724,033
of 22,759,618 outputs
Outputs from BMC Bioinformatics
#5,928
of 7,273 outputs
Outputs of similar age
#156,247
of 227,064 outputs
Outputs of similar age from BMC Bioinformatics
#101
of 149 outputs
Altmetric has tracked 22,759,618 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,273 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 227,064 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 149 others from the same source and published within six weeks on either side of this one. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.