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Natural genetic variation in transcriptome reflects network structure inferred with major effect mutations: insulin/TOR and associated phenotypes in Drosophila melanogaster

Overview of attention for article published in BMC Genomics, March 2009
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Title
Natural genetic variation in transcriptome reflects network structure inferred with major effect mutations: insulin/TOR and associated phenotypes in Drosophila melanogaster
Published in
BMC Genomics, March 2009
DOI 10.1186/1471-2164-10-124
Pubmed ID
Authors

Sergey V Nuzhdin, Jennifer A Brisson, Andrew Pickering, Marta L Wayne, Lawrence G Harshman, Lauren M McIntyre

Abstract

A molecular process based genotype-to-phenotype map will ultimately enable us to predict how genetic variation among individuals results in phenotypic alterations. Building such a map is, however, far from straightforward. It requires understanding how molecular variation re-shapes developmental and metabolic networks, and how the functional state of these networks modifies phenotypes in genotype specific way. We focus on the latter problem by describing genetic variation in transcript levels of genes in the InR/TOR pathway among 72 Drosophila melanogaster genotypes.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 5%
Portugal 1 2%
Germany 1 2%
Unknown 50 91%

Demographic breakdown

Readers by professional status Count As %
Researcher 20 36%
Student > Ph. D. Student 17 31%
Professor > Associate Professor 6 11%
Professor 3 5%
Student > Postgraduate 2 4%
Other 3 5%
Unknown 4 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 40 73%
Biochemistry, Genetics and Molecular Biology 6 11%
Medicine and Dentistry 2 4%
Business, Management and Accounting 1 2%
Psychology 1 2%
Other 1 2%
Unknown 4 7%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 August 2014.
All research outputs
#20,656,820
of 25,374,647 outputs
Outputs from BMC Genomics
#8,709
of 11,244 outputs
Outputs of similar age
#98,686
of 106,863 outputs
Outputs of similar age from BMC Genomics
#40
of 42 outputs
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