Title |
Characterization of a genetic mouse model of lung cancer: a promise to identify Non-Small Cell Lung Cancer therapeutic targets and biomarkers
|
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Published in |
BMC Genomics, May 2014
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DOI | 10.1186/1471-2164-15-s3-s1 |
Pubmed ID | |
Authors |
Federica Riccardo, Maddalena Arigoni, Genny Buson, Elisa Zago, Manuela Iezzi, Dario Livio Longo, Matteo Carrara, Alessandra Fiore, Simona Nuzzo, Silvio Bicciato, Patrizia Nanni, Lorena Landuzzi, Federica Cavallo, Raffaele Calogero, Elena Quaglino |
Abstract |
Non-small cell lung cancer (NSCLC) accounts for 81% of all cases of lung cancer and they are often fatal because 60% of the patients are diagnosed at an advanced stage. Besides the need for earlier diagnosis, there is a high need for additional effective therapies. In this work, we investigated the feasibility of a lung cancer progression mouse model, mimicking features of human aggressive NSCLC, as biological reservoir for potential therapeutic targets and biomarkers. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 53 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 13 | 25% |
Researcher | 11 | 21% |
Student > Bachelor | 8 | 15% |
Other | 4 | 8% |
Professor | 3 | 6% |
Other | 4 | 8% |
Unknown | 10 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 12 | 23% |
Agricultural and Biological Sciences | 10 | 19% |
Medicine and Dentistry | 10 | 19% |
Immunology and Microbiology | 4 | 8% |
Social Sciences | 2 | 4% |
Other | 4 | 8% |
Unknown | 11 | 21% |