Title |
Toxin production in a rare and genetically remote cluster of strains of the Bacillus cereus group
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Published in |
BMC Microbiology, May 2007
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DOI | 10.1186/1471-2180-7-43 |
Pubmed ID | |
Authors |
Annette Fagerlund, Julien Brillard, Rainer Fürst, Marie-Hélène Guinebretière, Per Einar Granum |
Abstract |
Three enterotoxins are implicated in diarrhoeal food poisoning due to Bacillus cereus: Haemolysin BL (Hbl), Non-haemolytic enterotoxin (Nhe), and Cytotoxin K (CytK). Toxin gene profiling and assays for detection of toxin-producing stains have been used in attempts to evaluate the enterotoxic potential of B. cereus group strains. B. cereus strain NVH 391/98, isolated from a case of fatal enteritis, was genetically remote from other B. cereus group strains. This strain lacked the genes encoding Hbl and Nhe, but contains CytK-1. The high virulence of this strain is thought to be due to the greater cytotoxic activity of CytK-1 compared to CytK-2, and to a high level of cytK expression. To date, only three strains containing cytK-1 have been identified; B. cereus strains NVH 391/98, NVH 883/00, and INRA AF2. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 2% |
Mexico | 1 | 2% |
India | 1 | 2% |
Unknown | 43 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 11 | 24% |
Student > Ph. D. Student | 10 | 22% |
Student > Master | 7 | 15% |
Student > Bachelor | 3 | 7% |
Professor > Associate Professor | 2 | 4% |
Other | 4 | 9% |
Unknown | 9 | 20% |
Readers by discipline | Count | As % |
---|---|---|
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Biochemistry, Genetics and Molecular Biology | 5 | 11% |
Immunology and Microbiology | 3 | 7% |
Environmental Science | 2 | 4% |
Neuroscience | 1 | 2% |
Other | 1 | 2% |
Unknown | 10 | 22% |