Title |
Complement C3 serum levels in anorexia nervosa: a potential biomarker for the severity of disease?
|
---|---|
Published in |
Annals of General Psychiatry, May 2011
|
DOI | 10.1186/1744-859x-10-16 |
Pubmed ID | |
Authors |
Michael A Flierl, Jennifer L Gaudiani, Allison L Sabel, Carlin S Long, Philip F Stahel, Philip S Mehler |
Abstract |
Anorexia nervosa carries the highest mortality rate of any psychiatric disorder. Even the most critically ill anorexic patients may present with normal 'standard' laboratory values, underscoring the need for a new sensitive biomarker. The complement cascade, a major component of innate immunity, represents a driving force in the pathophysiology of multiple inflammatory disorders. The role of complement in anorexia nervosa remains poorly understood. The present study was designed to evaluate the role of complement C3 levels, the extent of complement activation and of complement hemolytic activity in serum, as potential new biomarkers for the severity of anorexia nervosa. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 33% |
France | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 2 | 67% |
Members of the public | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 45 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Other | 7 | 16% |
Researcher | 7 | 16% |
Student > Master | 6 | 13% |
Student > Bachelor | 4 | 9% |
Student > Ph. D. Student | 3 | 7% |
Other | 10 | 22% |
Unknown | 8 | 18% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 14 | 31% |
Psychology | 5 | 11% |
Agricultural and Biological Sciences | 3 | 7% |
Nursing and Health Professions | 3 | 7% |
Computer Science | 1 | 2% |
Other | 8 | 18% |
Unknown | 11 | 24% |