Title |
The Unculturables: targeted isolation of bacterial species associated with canine periodontal health or disease from dental plaque
|
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Published in |
BMC Microbiology, August 2014
|
DOI | 10.1186/1471-2180-14-196 |
Pubmed ID | |
Authors |
Ian J Davis, Christopher Bull, Alexander Horsfall, Ian Morley, Stephen Harris |
Abstract |
The current inability to culture the entirety of observed bacteria is well known and with the advent of ever more powerful molecular tools, that can survey bacterial communities at previously unattainable depth, the gap in our capacity to culture and define all of these species increases exponentially. This gap has essentially become the rate limiting step in determining how the knowledge of which species are present in a sample can be applied to understand the role of these species in an ecosystem or disease process. A case in point is periodontal disease, which is the most widespread oral disease in dogs. If untreated the disease results in significant pain, eventual loss of the dentition and potentially an increased risk of systemic diseases. Previous molecular based studies have identified the bacterial species associated with periodontal disease in dogs; however without cultured strains from many of these species it has not been possible to study whether they play a role in the disease process. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 25% |
Venezuela, Bolivarian Republic of | 1 | 25% |
Unknown | 2 | 50% |
Demographic breakdown
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Scientists | 1 | 25% |
Mendeley readers
Geographical breakdown
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United Kingdom | 1 | 1% |
United States | 1 | 1% |
India | 1 | 1% |
Netherlands | 1 | 1% |
Unknown | 64 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 12 | 18% |
Student > Bachelor | 10 | 15% |
Student > Master | 10 | 15% |
Student > Ph. D. Student | 7 | 10% |
Other | 4 | 6% |
Other | 10 | 15% |
Unknown | 15 | 22% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 11 | 16% |
Veterinary Science and Veterinary Medicine | 9 | 13% |
Immunology and Microbiology | 7 | 10% |
Biochemistry, Genetics and Molecular Biology | 6 | 9% |
Other | 5 | 7% |
Unknown | 16 | 24% |