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The extracellular matrix protein mindin as a novel adjuvant elicits stronger immune responses for rBAG1, rSRS4 and rSRS9 antigens of Toxoplasma gondiiin BALB/c mice

Overview of attention for article published in BMC Infectious Diseases, August 2014
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1 tweeter

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Title
The extracellular matrix protein mindin as a novel adjuvant elicits stronger immune responses for rBAG1, rSRS4 and rSRS9 antigens of Toxoplasma gondiiin BALB/c mice
Published in
BMC Infectious Diseases, August 2014
DOI 10.1186/1471-2334-14-429
Pubmed ID
Authors

Xiaojing Sun, Mei, Xu Zhang, Fusong Han, Boyin Jia, Xiaoyan Wei, Zhiguang Chang, Huijun Lu, Jigang Yin, Qijun Chen, Ning Jiang

Abstract

Vaccines are the most effective agents to control infections. However, recombinant vaccines often do not elicit strong immune responses. Protein antigens combined with proper adjuvants have been widely used to induce immune responses, especially the humoral immune responses, against various pathogens, including parasites. The extracellular matrix protein mindin has been recognised as an immune facilitator for initiating innate immune responses. It has therefore been expected to be a potentially potent adjuvant in the development of novel vaccines. The aim of this study was to investigate whether mindin could facilitate the induction of antigen-specific immune responses to recombinant antigens (rBAG1, rSRS4 and rSRS9) of Toxoplasma gondii in BALB/c mice.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 27 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 26%
Student > Ph. D. Student 6 22%
Researcher 5 19%
Student > Bachelor 2 7%
Professor 1 4%
Other 2 7%
Unknown 4 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 30%
Veterinary Science and Veterinary Medicine 4 15%
Medicine and Dentistry 4 15%
Biochemistry, Genetics and Molecular Biology 3 11%
Energy 1 4%
Other 2 7%
Unknown 5 19%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 October 2014.
All research outputs
#7,545,568
of 8,702,492 outputs
Outputs from BMC Infectious Diseases
#3,453
of 3,848 outputs
Outputs of similar age
#147,786
of 182,390 outputs
Outputs of similar age from BMC Infectious Diseases
#144
of 153 outputs
Altmetric has tracked 8,702,492 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,848 research outputs from this source. They receive a mean Attention Score of 4.1. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 182,390 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 153 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.