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Selective internal radiotherapy (SIRT) versus transarterial chemoembolization (TACE) for the treatment of intrahepatic cholangiocellular carcinoma (CCC): study protocol for a randomized controlled…

Overview of attention for article published in Trials, August 2014
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Title
Selective internal radiotherapy (SIRT) versus transarterial chemoembolization (TACE) for the treatment of intrahepatic cholangiocellular carcinoma (CCC): study protocol for a randomized controlled trial
Published in
Trials, August 2014
DOI 10.1186/1745-6215-15-311
Pubmed ID
Authors

Roman Kloeckner, Christian Ruckes, Kai Kronfeld, Marcus Alexander Wörns, Arndt Weinmann, Peter Robert Galle, Hauke Lang, Gerd Otto, Waltraud Eichhorn, Mathias Schreckenberger, Christoph Dueber, Michael Bernhard Pitton

Abstract

Cholangiocellular carcinoma is the second most common primary liver cancer after hepatocellular carcinoma. Over the last 30 years, the incidence of intrahepatic cholangiocellular carcinoma has risen continuously worldwide. Meanwhile, the intrahepatic cholangiocellular carcinoma has become more common than the extrahepatic growth type and currently accounts for 10-15% of all primary hepatic malignancies. Intrahepatic cholangiocellular carcinoma is typically diagnosed in advanced stages due to late clinical symptoms and an absence of classic risk factors. A late diagnosis precludes curative surgical resection. There is evidence that transarterial chemoembolization leads to better local tumor control and prolongs survival compared to systemic chemotherapy. New data indicates that selective internal radiotherapy, also referred to as radioembolization, provides promising results for treating intrahepatic cholangiocellular carcinoma.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 62 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 2%
Brazil 1 2%
Unknown 60 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 12 19%
Researcher 8 13%
Student > Ph. D. Student 7 11%
Student > Doctoral Student 4 6%
Student > Bachelor 4 6%
Other 10 16%
Unknown 17 27%
Readers by discipline Count As %
Medicine and Dentistry 32 52%
Biochemistry, Genetics and Molecular Biology 4 6%
Nursing and Health Professions 2 3%
Engineering 2 3%
Agricultural and Biological Sciences 1 2%
Other 3 5%
Unknown 18 29%