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An evaluation of contaminated complete feed as a vehicle for porcine epidemic diarrhea virus infection of naïve pigs following consumption via natural feeding behavior: proof of concept

Overview of attention for article published in BMC Veterinary Research, August 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (94th percentile)
  • High Attention Score compared to outputs of the same age and source (95th percentile)

Mentioned by

news
1 news outlet
blogs
1 blog
policy
1 policy source
twitter
5 X users
patent
2 patents

Citations

dimensions_citation
139 Dimensions

Readers on

mendeley
139 Mendeley
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Title
An evaluation of contaminated complete feed as a vehicle for porcine epidemic diarrhea virus infection of naïve pigs following consumption via natural feeding behavior: proof of concept
Published in
BMC Veterinary Research, August 2014
DOI 10.1186/s12917-014-0176-9
Pubmed ID
Authors

Scott Dee, Travis Clement, Adam Schelkopf, Joel Nerem, David Knudsen, Jane Christopher-Hennings, Eric Nelson

Abstract

BackgroundSince its initial detection in May 2013, porcine epidemic diarrhea virus (PEDV) has spread rapidly throughout the US swine industry. Initially, contaminated feed was proposed as a risk factor for PEDV; however, data were not available to support this theory. Here we provide proof of concept of this risk by describing a novel means for recovering PEDV-contaminated complete feed material from commercial swine sites and conducting an in vivo experiment to prove its infectivity.ResultsFor on-farm detection of PEDV RNA in feed, paint rollers were used to collect material from at-risk feed bins from 3 clinically affected breeding herds. This material was tested by PCR and determined to be positive for PEDV-RNA (Ct¿=¿19.50-22.20 range). To test infectivity, this material was pooled (Ct¿=¿20.65) and a Treatment group of 3-week old PEDV-naïve piglets were allowed to consume it via natural feeding behavior. For the purpose of a Positive control, piglets were allowed to ingest feed spiked with stock PEDV (Ct¿=¿18.23) while the negative control group received PEDV-free feed. Clinical signs of PEDV infection (vomiting and diarrhea) and viral shedding were observed in both the Positive control and Treatment group¿ post-consumption with virus and microscopic lesions detected in intestinal samples No evidence of infection was observed in the Negative controls.ConclusionsThese data provide proof of concept that contaminated complete feed can serve as a vehicle for PEDV infection of naïve pigs using natural feeding behavior.

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X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 139 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 1%
Mexico 1 <1%
Canada 1 <1%
Unknown 135 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 24 17%
Student > Master 24 17%
Student > Ph. D. Student 16 12%
Student > Bachelor 13 9%
Other 7 5%
Other 29 21%
Unknown 26 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 36 26%
Veterinary Science and Veterinary Medicine 33 24%
Medicine and Dentistry 13 9%
Biochemistry, Genetics and Molecular Biology 7 5%
Computer Science 3 2%
Other 13 9%
Unknown 34 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 28. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 January 2023.
All research outputs
#1,252,294
of 23,577,654 outputs
Outputs from BMC Veterinary Research
#59
of 3,101 outputs
Outputs of similar age
#13,216
of 231,841 outputs
Outputs of similar age from BMC Veterinary Research
#2
of 43 outputs
Altmetric has tracked 23,577,654 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,101 research outputs from this source. They receive a mean Attention Score of 4.1. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 231,841 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 43 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.