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Comparative analysis of hapalindole, ambiguine and welwitindolinone gene clusters and reconstitution of indole-isonitrile biosynthesis from cyanobacteria

Overview of attention for article published in BMC Microbiology, August 2014
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  • Above-average Attention Score compared to outputs of the same age and source (64th percentile)

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3 X users

Citations

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86 Mendeley
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Title
Comparative analysis of hapalindole, ambiguine and welwitindolinone gene clusters and reconstitution of indole-isonitrile biosynthesis from cyanobacteria
Published in
BMC Microbiology, August 2014
DOI 10.1186/s12866-014-0213-7
Pubmed ID
Authors

Melinda L Micallef, Deepti Sharma, Brittney M Bunn, Lena Gerwick, Rajesh Viswanathan, Michelle C Moffitt

Abstract

The hapalindole-type family of natural products is a group of hybrid isoprenoid-indole alkaloids, produced solely by members of the Subsection V cyanobacterial strains. This family broadly includes the hapalindoles, welwitindolinones, fisherindoles and ambiguines amongst others, all of which have an isonitrile- or isothiocyanate-containing indole alkaloid skeleton, with a cyclized isoprene unit. The hapalindoles are diversified into the welwitindolinones, fischerindoles and ambiguines through the employment of tailoring oxygenase, methyltransferase and prenyltransferase enzymes. We compare the genetic basis for the biosynthesis of this diverse group of natural products and identify key early biosynthetic intermediates.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Peru 1 1%
South Africa 1 1%
Unknown 84 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 19%
Student > Master 13 15%
Researcher 12 14%
Student > Bachelor 11 13%
Student > Doctoral Student 5 6%
Other 14 16%
Unknown 15 17%
Readers by discipline Count As %
Chemistry 22 26%
Agricultural and Biological Sciences 19 22%
Biochemistry, Genetics and Molecular Biology 14 16%
Environmental Science 4 5%
Pharmacology, Toxicology and Pharmaceutical Science 3 3%
Other 5 6%
Unknown 19 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 November 2019.
All research outputs
#13,410,980
of 22,759,618 outputs
Outputs from BMC Microbiology
#1,269
of 3,184 outputs
Outputs of similar age
#109,215
of 229,515 outputs
Outputs of similar age from BMC Microbiology
#15
of 42 outputs
Altmetric has tracked 22,759,618 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,184 research outputs from this source. They receive a mean Attention Score of 4.1. This one has gotten more attention than average, scoring higher than 58% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 229,515 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.
We're also able to compare this research output to 42 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.