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A Rb1 promoter variant with reduced activity contributes to osteosarcoma susceptibility in irradiated mice

Overview of attention for article published in Molecular Cancer, August 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (94th percentile)
  • High Attention Score compared to outputs of the same age and source (95th percentile)

Mentioned by

news
3 news outlets
blogs
1 blog

Citations

dimensions_citation
14 Dimensions

Readers on

mendeley
26 Mendeley
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Title
A Rb1 promoter variant with reduced activity contributes to osteosarcoma susceptibility in irradiated mice
Published in
Molecular Cancer, August 2014
DOI 10.1186/1476-4598-13-182
Pubmed ID
Authors

Michael Rosemann, Iria Gonzalez-Vasconcellos, Tanja Domke, Virginija Kuosaite, Ralf Schneider, Markus Kremer, Jack Favor, Michaela Nathrath, Michael J Atkinson

Abstract

Syndromic forms of osteosarcoma (OS) account for less than 10% of all recorded cases of this malignancy. An individual OS predisposition is also possible by the inheritance of low penetrance alleles of tumor susceptibility genes, usually without evidence of a syndromic condition. Genetic variants involved in such a non-syndromic form of tumor predisposition are difficult to identify, given the low incidence of osteosarcoma cases and the genetic heterogeneity of patients. We recently mapped a major OS susceptibility QTL to mouse chromosome 14 by comparing alpha-radiation induced osteosarcoma in mouse strains which differ in their tumor susceptibility.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 26 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 15%
Student > Bachelor 4 15%
Researcher 4 15%
Student > Master 3 12%
Student > Doctoral Student 2 8%
Other 4 15%
Unknown 5 19%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 8 31%
Medicine and Dentistry 5 19%
Agricultural and Biological Sciences 4 15%
Nursing and Health Professions 1 4%
Computer Science 1 4%
Other 1 4%
Unknown 6 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 28. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 August 2014.
All research outputs
#1,404,379
of 25,371,288 outputs
Outputs from Molecular Cancer
#75
of 1,918 outputs
Outputs of similar age
#13,857
of 241,340 outputs
Outputs of similar age from Molecular Cancer
#2
of 46 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,918 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 241,340 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 46 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.