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Lipoteichoic acid is an important microbe-associated molecular pattern of Lactobacillus rhamnosus GG

Overview of attention for article published in Microbial Cell Factories, December 2012
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Title
Lipoteichoic acid is an important microbe-associated molecular pattern of Lactobacillus rhamnosus GG
Published in
Microbial Cell Factories, December 2012
DOI 10.1186/1475-2859-11-161
Pubmed ID
Authors

Ingmar JJ Claes, Marijke E Segers, Tine LA Verhoeven, Michiel Dusselier, Bert F Sels, Sigrid CJ De Keersmaecker, Jos Vanderleyden, Sarah Lebeer

Abstract

Probiotic bacteria are increasingly used as immunomodulatory agents. Yet detailed molecular knowledge on the immunomodulatory molecules of these bacteria is lagging behind. Lipoteichoic acid (LTA) is considered a major microbe-associated molecular pattern (MAMP) of Gram-positive bacteria. However, many details and quantitative data on its immune signalling capacity are still unknown, especially in beneficial bacteria. Recently, we have demonstrated that a dltD mutant of the model probiotic Lactobacillus rhamnosus GG (LGG), having modified LTA molecules, has an enhanced probiotic efficacy in a DSS-induced colitis model as compared to wild-type.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 120 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 120 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 22 18%
Researcher 21 18%
Student > Master 12 10%
Student > Doctoral Student 9 8%
Student > Postgraduate 5 4%
Other 13 11%
Unknown 38 32%
Readers by discipline Count As %
Agricultural and Biological Sciences 25 21%
Immunology and Microbiology 22 18%
Biochemistry, Genetics and Molecular Biology 13 11%
Medicine and Dentistry 10 8%
Chemistry 4 3%
Other 9 8%
Unknown 37 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 August 2014.
All research outputs
#20,234,388
of 22,760,687 outputs
Outputs from Microbial Cell Factories
#1,359
of 1,595 outputs
Outputs of similar age
#247,682
of 279,269 outputs
Outputs of similar age from Microbial Cell Factories
#33
of 33 outputs
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So far Altmetric has tracked 1,595 research outputs from this source. They receive a mean Attention Score of 4.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 33 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.