Title |
Identification and characterization of Dicer1e, a Dicer1 protein variant, in oral cancer cells
|
---|---|
Published in |
Molecular Cancer, August 2014
|
DOI | 10.1186/1476-4598-13-190 |
Pubmed ID | |
Authors |
Liliana P Cantini, Lourdes M Andino, Christopher C Attaway, Betsy Butler, Anca Dumitriu, Aaron Blackshaw, Andrew Jakymiw |
Abstract |
The human dicer1 gene has been predicted to produce several mRNA variants that encode truncated Dicer1 proteins of varying lengths. One of these Dicer1 variants, Dicer1e, was recently found to be differentially expressed in breast cancer cells. Because the expression and function of the Dicer1e protein variant has not been well characterized and the underlying molecular mechanisms for the development of oral squamous cell carcinomas (OSCCs) are poorly understood, the present study sought to characterize the biological role of Dicer1e and determine its relationship, if any, to OSCC pathogenesis. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Scientists | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 20 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 6 | 30% |
Student > Master | 4 | 20% |
Student > Ph. D. Student | 2 | 10% |
Student > Doctoral Student | 1 | 5% |
Other | 1 | 5% |
Other | 3 | 15% |
Unknown | 3 | 15% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 7 | 35% |
Agricultural and Biological Sciences | 6 | 30% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 10% |
Biochemistry, Genetics and Molecular Biology | 1 | 5% |
Unknown | 4 | 20% |