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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Cardiovascular protection of magnolol: cell-type specificity and dose-related effects
|
|---|---|
| Published in |
Journal of Biomedical Science, July 2012
|
| DOI | 10.1186/1423-0127-19-70 |
| Pubmed ID | |
| Authors |
Jennifer Hui-Chun Ho, Chuang-Ye Hong |
| Abstract |
Magnolia officinalis has been widely used in traditional Chinese medicine. Magnolol, an active component isolated from Magnolia officinalis, is known to be a cardiovascular protector since 1994. The multiplex mechanisms of magnolol on cardiovascular protection depends on cell types and dosages, and will be reviewed and discussed in this article. Magnolol under low and moderate dosage possesses the ability to protect heart from ischemic/reperfusion injury, reduces atherosclerotic change, protects endothelial cell against apoptosis and inhibits neutrophil-endothelial adhesion. The moderate to high concentration of magnolol mainly acts on smooth muscle cells and platelets. Magnolol induces apoptosis in vascular smooth muscle cells at moderate concentration and inhibits proliferation at moderate and high concentration. High concentration of magnolol also abrogates platelet activation, aggregation and thrombus formation. Magnolol also serves as an smooth muscle relaxant only upon the high concentration. Oral intake of magnolol to reach the therapeutic level for cardiovascular protection is applicable, thus makes magnolol an agent of great potential for preventing cardiovascular diseases in high-risk patients. |
X Demographics
The data shown below were collected from the profiles of 23 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 17% |
| Spain | 1 | 4% |
| Canada | 1 | 4% |
| United Kingdom | 1 | 4% |
| Unknown | 16 | 70% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 19 | 83% |
| Scientists | 3 | 13% |
| Practitioners (doctors, other healthcare professionals) | 1 | 4% |
Mendeley readers
The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 3% |
| Unknown | 37 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 7 | 18% |
| Student > Doctoral Student | 5 | 13% |
| Other | 3 | 8% |
| Student > Bachelor | 3 | 8% |
| Student > Ph. D. Student | 2 | 5% |
| Other | 4 | 11% |
| Unknown | 14 | 37% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 6 | 16% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 13% |
| Medicine and Dentistry | 5 | 13% |
| Biochemistry, Genetics and Molecular Biology | 4 | 11% |
| Sports and Recreations | 2 | 5% |
| Other | 1 | 3% |
| Unknown | 15 | 39% |
Attention Score in Context
This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 August 2023.
All research outputs
#2,303,963
of 25,736,439 outputs
Outputs from Journal of Biomedical Science
#86
of 1,112 outputs
Outputs of similar age
#14,333
of 179,505 outputs
Outputs of similar age from Journal of Biomedical Science
#2
of 13 outputs
Altmetric has tracked 25,736,439 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,112 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.1. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 179,505 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.