Title |
Effects of body weight and alcohol consumption on insulin sensitivity
|
---|---|
Published in |
Nutrition Journal, March 2010
|
DOI | 10.1186/1475-2891-9-14 |
Pubmed ID | |
Authors |
Qiwei X Paulson, Jina Hong, Valerie B Holcomb, Nomeli P Nunez |
Abstract |
Obesity is a risk factor for the development of insulin resistance, which can eventually lead to type-2 diabetes. Alcohol consumption is a protective factor against insulin resistance, and thus protects against the development of type-2 diabetes. The mechanism by which alcohol protects against the development of type-2 diabetes is not well known. To determine the mechanism by which alcohol improves insulin sensitivity, we fed water or alcohol to lean, control, and obese mice. The aim of this study was to determine whether alcohol consumption and body weights affect overlapping metabolic pathways and to identify specific target genes that are regulated in these pathways. |
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Geographical breakdown
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Netherlands | 1 | 13% |
Brazil | 1 | 13% |
Unknown | 4 | 50% |
Demographic breakdown
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Members of the public | 5 | 63% |
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Mendeley readers
Geographical breakdown
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Unknown | 80 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 14 | 17% |
Researcher | 10 | 12% |
Student > Ph. D. Student | 10 | 12% |
Student > Bachelor | 7 | 9% |
Student > Postgraduate | 4 | 5% |
Other | 18 | 22% |
Unknown | 18 | 22% |
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Nursing and Health Professions | 4 | 5% |
Other | 13 | 16% |
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