Title |
The relationship between lymphatic vascular density and vascular endothelial growth factor A (VEGF-A) expression with clinical-pathological features and survival in pancreatic adenocarcinomas
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Published in |
Diagnostic Pathology, October 2013
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DOI | 10.1186/1746-1596-8-170 |
Pubmed ID | |
Authors |
Verônica A Zorgetto, Giórgia G Silveira, João Paulo Oliveira-Costa, Danilo F Soave, Fernando A Soares, Alfredo Ribeiro-Silva |
Abstract |
Pancreatic cancer is a rare tumor with an extremely low survival rate. Its known risk factors include the chronic use of tobacco and excessive alcohol consumption and the presence of chronic inflammatory diseases, such as pancreatitis and type 2 diabetes. Angiogenesis and lymphangiogenesis, which have been the focus of recent research, are considered prognostic factors for cancer development. Knowing the angiogenic and lymphangiogenic profiles of a tumor may provide new insights for designing treatments according to the different properties of the tumor. The aim of this study was to evaluate the density of blood and lymphatic vessels, and the expression of VEGF-A, in pancreatic adenocarcinomas, as well as the relationship between blood and lymphatic vascular density and the prognostically important clinical-pathological features of pancreatic tumors. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 45 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 11 | 24% |
Student > Bachelor | 7 | 16% |
Researcher | 4 | 9% |
Student > Doctoral Student | 4 | 9% |
Student > Ph. D. Student | 4 | 9% |
Other | 8 | 18% |
Unknown | 7 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 16 | 36% |
Biochemistry, Genetics and Molecular Biology | 4 | 9% |
Psychology | 4 | 9% |
Agricultural and Biological Sciences | 3 | 7% |
Nursing and Health Professions | 2 | 4% |
Other | 6 | 13% |
Unknown | 10 | 22% |