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OX26/CTX-conjugated PEGylated liposome as a dual-targeting gene delivery system for brain glioma

Overview of attention for article published in Molecular Cancer, August 2014
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Title
OX26/CTX-conjugated PEGylated liposome as a dual-targeting gene delivery system for brain glioma
Published in
Molecular Cancer, August 2014
DOI 10.1186/1476-4598-13-191
Pubmed ID
Authors

Pei-jian Yue, Lei He, Shu-wei Qiu, Yi Li, Yi-ji Liao, Xiang-pen Li, Dan Xie, Ying Peng

Abstract

The successful gene delivery into the brain is a major challenge due to the presence of the blood-brain barrier (BBB). In order to transport plasmid DNA across the BBB and target the brain glioma, the PEGylated liposomes (PLs) modified with OX26 and chlorotoxin (CTX) were developed as a dual-targeting gene delivery system, and the therapeutic efficacy of OX26/CTX-PL/pC27 against glioma was evaluated using in vitro and in vivo experimental models.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 75 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 17%
Student > Master 11 15%
Researcher 8 11%
Student > Doctoral Student 7 9%
Student > Bachelor 6 8%
Other 12 16%
Unknown 18 24%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 17 23%
Agricultural and Biological Sciences 8 11%
Medicine and Dentistry 5 7%
Chemistry 5 7%
Biochemistry, Genetics and Molecular Biology 4 5%
Other 7 9%
Unknown 29 39%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 August 2014.
All research outputs
#20,234,388
of 22,760,687 outputs
Outputs from Molecular Cancer
#1,478
of 1,718 outputs
Outputs of similar age
#194,296
of 231,138 outputs
Outputs of similar age from Molecular Cancer
#41
of 43 outputs
Altmetric has tracked 22,760,687 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,718 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 43 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.