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The significance of the F variant of alpha-1-antitrypsin and unique case report of a PiFF homozygote

Overview of attention for article published in BMC Pulmonary Medicine, August 2014
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (71st percentile)
  • Good Attention Score compared to outputs of the same age and source (75th percentile)

Mentioned by

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3 Facebook pages
wikipedia
1 Wikipedia page

Citations

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27 Dimensions

Readers on

mendeley
36 Mendeley
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Title
The significance of the F variant of alpha-1-antitrypsin and unique case report of a PiFF homozygote
Published in
BMC Pulmonary Medicine, August 2014
DOI 10.1186/1471-2466-14-132
Pubmed ID
Authors

Nicola Jane Sinden, Firas Koura, Robert Andrew Stockley

Abstract

Inheritance of the F variant of alpha-1-antitrypsin is associated with normal circulating protein levels, but it is believed to be dysfunctional in its ability to inhibit neutrophil elastase and therefore has been implicated as a susceptibility factor for the development of emphysema. In this study, its functional characteristics were determined following the identification of a unique patient with the PiFF phenotype, and the implications as a susceptibility factor for emphysema are considered both in homozygotes and heterozygotes.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 3%
Unknown 35 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 14%
Researcher 5 14%
Student > Bachelor 4 11%
Student > Doctoral Student 3 8%
Other 2 6%
Other 4 11%
Unknown 13 36%
Readers by discipline Count As %
Medicine and Dentistry 13 36%
Agricultural and Biological Sciences 3 8%
Immunology and Microbiology 2 6%
Biochemistry, Genetics and Molecular Biology 1 3%
Nursing and Health Professions 1 3%
Other 3 8%
Unknown 13 36%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 June 2022.
All research outputs
#6,767,639
of 22,721,584 outputs
Outputs from BMC Pulmonary Medicine
#485
of 1,900 outputs
Outputs of similar age
#64,667
of 230,182 outputs
Outputs of similar age from BMC Pulmonary Medicine
#9
of 36 outputs
Altmetric has tracked 22,721,584 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 1,900 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 230,182 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 36 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.