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Regulatory and coding genome regions are enriched for trait associated variants in dairy and beef cattle

Overview of attention for article published in BMC Genomics, June 2014
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Title
Regulatory and coding genome regions are enriched for trait associated variants in dairy and beef cattle
Published in
BMC Genomics, June 2014
DOI 10.1186/1471-2164-15-436
Pubmed ID
Authors

Lambros Koufariotis, Yi-Ping Phoebe Chen, Sunduimijid Bolormaa, Ben J Hayes

Abstract

In livestock, as in humans, the number of genetic variants that can be tested for association with complex quantitative traits, or used in genomic predictions, is increasing exponentially as whole genome sequencing becomes more common. The power to identify variants associated with traits, particularly those of small effects, could be increased if certain regions of the genome were known a priori to be enriched for associations. Here, we investigate whether twelve genomic annotation classes were enriched or depleted for significant associations in genome wide association studies for complex traits in beef and dairy cattle. We also describe a variance component approach to determine the proportion of genetic variance captured by each annotation class.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Canada 1 2%
Unknown 47 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 16 33%
Student > Ph. D. Student 14 29%
Student > Master 4 8%
Other 3 6%
Student > Doctoral Student 1 2%
Other 2 4%
Unknown 8 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 28 58%
Biochemistry, Genetics and Molecular Biology 9 19%
Veterinary Science and Veterinary Medicine 1 2%
Medicine and Dentistry 1 2%
Unknown 9 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 November 2015.
All research outputs
#20,657,128
of 25,374,917 outputs
Outputs from BMC Genomics
#8,709
of 11,244 outputs
Outputs of similar age
#178,023
of 242,856 outputs
Outputs of similar age from BMC Genomics
#197
of 281 outputs
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