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Mindfulness-based cognitive therapy versus psychoeducational intervention in bipolar outpatients with sub-threshold depressive symptoms: a randomized controlled trial

Overview of attention for article published in BMC Psychiatry, August 2014
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Title
Mindfulness-based cognitive therapy versus psychoeducational intervention in bipolar outpatients with sub-threshold depressive symptoms: a randomized controlled trial
Published in
BMC Psychiatry, August 2014
DOI 10.1186/s12888-014-0215-x
Pubmed ID
Authors

Guillermo Lahera, Carmen Bayón, Maria Fe Bravo-Ortiz, Beatriz Rodríguez-Vega, Sara Barbeito, Margarita Sáenz, Caridad Avedillo, Rosa Villanueva, Amaia Ugarte, Ana González-Pinto, Consuelo de Dios

Abstract

BackgroundThe presence of depressive subsyndromal symptoms (SS) in bipolar disorder (BD) increases the risk of affective relapse and worsens social, cognitive functioning, and quality of life. Nonetheless, there are limited data on how to optimize the treatment of subthreshold depressive symptoms in BD. Mindfulness-Based Cognitive Therapy (MBCT) is a psychotherapeutic intervention that has been shown effective in unipolar depression. The assessment of its clinical effectiveness and its impact on biomarkers in bipolar disorder patients with subsyndromal depressive symptoms and psychopharmacological treatment is needed.Methods/designA randomized, multicenter, prospective, versus active comparator, evaluator-blinded clinical trial is proposed. Patients with BD and subclinical or mild depressive symptoms will be randomly allocated to: 1) MBCT added to psychopharmacological treatment; 2) a brief structured group psychoeducational intervention added to psychopharmacological treatment; 3) standard clinical management, including psychopharmacological treatment. Assessments will be conducted at screening, baseline, post-intervention (8 weeks) and 4 month follow-up post-intervention. The aim is to compare MBCT intervention versus a brief structured group psychoeducation. Our hypothesis is that MBCT will be more effective in reducing the subsyndromal depressive symptoms and will improve cognitive performance to a higher degree than the psychoeducational treatment. It is also hypothesized that a significant increase of BDNF levels will be found after the MBCT intervention.DiscussionThis is the first randomized controlled trial to evaluate the effects of MBCT compared to an active control group on depressive subthreshold depressive symptoms in patients with bipolar disorder.Trial registrationClinicalTrials.gov: NCT02133170. Registered 04/30/2014.

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The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 331 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 <1%
Singapore 1 <1%
Brazil 1 <1%
Unknown 328 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 46 14%
Student > Master 43 13%
Student > Doctoral Student 37 11%
Student > Bachelor 33 10%
Student > Ph. D. Student 29 9%
Other 67 20%
Unknown 76 23%
Readers by discipline Count As %
Psychology 110 33%
Medicine and Dentistry 58 18%
Nursing and Health Professions 24 7%
Social Sciences 21 6%
Neuroscience 8 2%
Other 25 8%
Unknown 85 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 September 2015.
All research outputs
#14,198,795
of 22,760,687 outputs
Outputs from BMC Psychiatry
#3,036
of 4,669 outputs
Outputs of similar age
#118,961
of 230,675 outputs
Outputs of similar age from BMC Psychiatry
#48
of 77 outputs
Altmetric has tracked 22,760,687 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,669 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.9. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
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We're also able to compare this research output to 77 others from the same source and published within six weeks on either side of this one. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.