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Variable NF-κB pathway responses in colon cancer cells treated with chemotherapeutic drugs

Overview of attention for article published in BMC Cancer, August 2014
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Title
Variable NF-κB pathway responses in colon cancer cells treated with chemotherapeutic drugs
Published in
BMC Cancer, August 2014
DOI 10.1186/1471-2407-14-599
Pubmed ID
Authors

Temesgen Samuel, Khalda Fadlalla, Dominique N Gales, Balananda DK Putcha, Upender Manne

Abstract

The nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway is activated in cells exposed to various stimuli, including those originating on the cell surface or in the nucleus. Activated NF-κB signaling is thought to enhance cell survival in response to these stimuli, which include chemotherapy and radiation. In the present effort, we determined which anticancer drugs preferentially activate NF-κB in colon cancer cells.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 45 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 36%
Other 4 9%
Researcher 4 9%
Professor > Associate Professor 3 7%
Student > Bachelor 3 7%
Other 6 13%
Unknown 9 20%
Readers by discipline Count As %
Medicine and Dentistry 8 18%
Biochemistry, Genetics and Molecular Biology 8 18%
Agricultural and Biological Sciences 8 18%
Immunology and Microbiology 3 7%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Other 5 11%
Unknown 11 24%