↓ Skip to main content

Chikungunya triggers an autophagic process which promotes viral replication

Overview of attention for article published in Virology Journal, September 2011
Altmetric Badge

Mentioned by

twitter
1 X user

Citations

dimensions_citation
93 Dimensions

Readers on

mendeley
137 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Chikungunya triggers an autophagic process which promotes viral replication
Published in
Virology Journal, September 2011
DOI 10.1186/1743-422x-8-432
Pubmed ID
Authors

Pascale Krejbich-Trotot, Bernard Gay, Ghislaine Li-Pat-Yuen, Jean-Jacques Hoarau, Marie-Christine Jaffar-Bandjee, Laurence Briant, Philippe Gasque, Mélanie Denizot

Abstract

Chikungunya Virus (ChikV) surprised by a massive re-emerging outbreak in Indian Ocean in 2006, reaching Europe in 2007 and exhibited exceptional severe physiopathology in infants and elderly patients. In this context, it is important to analyze the innate immune host responses triggered against ChikV. Autophagy has been shown to be an important component of the innate immune response and is involved in host defense elimination of different pathogens. However, the autophagic process was recently observed to be hijacked by virus for their own replication. Here we provide the first evidence that hallmarks of autophagy are specifically found in HEK.293 infected cells and are involved in ChikV replication.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 137 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 2%
Italy 1 <1%
Unknown 133 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 29 21%
Student > Master 21 15%
Researcher 16 12%
Student > Bachelor 16 12%
Student > Postgraduate 8 6%
Other 22 16%
Unknown 25 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 40 29%
Immunology and Microbiology 18 13%
Biochemistry, Genetics and Molecular Biology 18 13%
Medicine and Dentistry 11 8%
Neuroscience 3 2%
Other 16 12%
Unknown 31 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 September 2011.
All research outputs
#18,295,723
of 22,651,245 outputs
Outputs from Virology Journal
#2,417
of 3,022 outputs
Outputs of similar age
#103,976
of 125,702 outputs
Outputs of similar age from Virology Journal
#40
of 49 outputs
Altmetric has tracked 22,651,245 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,022 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.5. This one is in the 5th percentile – i.e., 5% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 125,702 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 49 others from the same source and published within six weeks on either side of this one. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.