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Efficacy of lidocaine in patients receiving palliative care with opioid-refractory cancer pain with a neuropathic component: study protocol for a randomized controlled study

Overview of attention for article published in Trials, August 2014
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Title
Efficacy of lidocaine in patients receiving palliative care with opioid-refractory cancer pain with a neuropathic component: study protocol for a randomized controlled study
Published in
Trials, August 2014
DOI 10.1186/1745-6215-15-318
Pubmed ID
Authors

Sébastien Salas, Pascal Auquier, Florence Duffaud, Stéphanie Ranque Garnier, Mélanie Deschamps, Stéphane Honoré, Patrick Sudour, Karine Baumstarck

Abstract

The management of patients suffering from opioid-refractory cancer pain with a neuropathic component remains an important challenge for healthcare workers. Only one retrospective study specifically reported the use of intravenous (IV) lidocaine amongst the palliative care unit population, however, the study found that there was a positive response to this therapy. These preliminary uncontrolled results need to be confirmed by randomized controlled trials. The primary objective of this study is to assess the analgesic efficacy of IV lidocaine in patients in palliative care suffering from opioid-refractory cancer pain with a neuropathic component. The secondary objectives are to assess the tolerance of, symptomatology, and patient satisfaction with the therapeutic approach.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 89 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 1 1%
Unknown 88 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 12%
Student > Master 10 11%
Student > Bachelor 9 10%
Student > Ph. D. Student 8 9%
Other 8 9%
Other 13 15%
Unknown 30 34%
Readers by discipline Count As %
Medicine and Dentistry 25 28%
Nursing and Health Professions 11 12%
Psychology 4 4%
Agricultural and Biological Sciences 2 2%
Biochemistry, Genetics and Molecular Biology 2 2%
Other 10 11%
Unknown 35 39%