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Toll-like receptors in the pathogenesis of human B cell malignancies

Overview of attention for article published in Journal of Hematology & Oncology, August 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

Mentioned by

news
1 news outlet
twitter
2 X users

Citations

dimensions_citation
46 Dimensions

Readers on

mendeley
124 Mendeley
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Title
Toll-like receptors in the pathogenesis of human B cell malignancies
Published in
Journal of Hematology & Oncology, August 2014
DOI 10.1186/s13045-014-0057-5
Pubmed ID
Authors

Johana M Isaza-Correa, Zheng Liang, Anke van den Berg, Arjan Diepstra, Lydia Visser

Abstract

Toll-like receptors (TLRs) are important players in B-cell activation, maturation and memory and may be involved in the pathogenesis of B-cell lymphomas. Accumulating studies show differential expression in this heterogeneous group of cancers. Stimulation with TLR specific ligands, or agonists of their ligands, leads to aberrant responses in the malignant B-cells. According to current data, TLRs can be implicated in malignant transformation, tumor progression and immune evasion processes. Most of the studies focused on multiple myeloma and chronic lymphocytic leukemia, but in the last decade the putative role of TLRs in other types of B-cell lymphomas has gained much interest. The aim of this review is to discuss recent findings on the role of TLRs in normal B cell functioning and their role in the pathogenesis of B-cell malignancies.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 124 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 1 <1%
Unknown 123 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 24 19%
Student > Ph. D. Student 22 18%
Student > Bachelor 13 10%
Student > Master 12 10%
Student > Doctoral Student 7 6%
Other 16 13%
Unknown 30 24%
Readers by discipline Count As %
Agricultural and Biological Sciences 27 22%
Biochemistry, Genetics and Molecular Biology 21 17%
Medicine and Dentistry 18 15%
Immunology and Microbiology 18 15%
Pharmacology, Toxicology and Pharmaceutical Science 2 2%
Other 8 6%
Unknown 30 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 December 2023.
All research outputs
#3,203,550
of 25,010,497 outputs
Outputs from Journal of Hematology & Oncology
#266
of 1,275 outputs
Outputs of similar age
#31,017
of 237,113 outputs
Outputs of similar age from Journal of Hematology & Oncology
#2
of 11 outputs
Altmetric has tracked 25,010,497 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,275 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.4. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 237,113 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.