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Chemical glycosylation of cytochrome c improves physical and chemical protein stability

Overview of attention for article published in BMC Molecular and Cell Biology, August 2014
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Title
Chemical glycosylation of cytochrome c improves physical and chemical protein stability
Published in
BMC Molecular and Cell Biology, August 2014
DOI 10.1186/1471-2091-15-16
Pubmed ID
Authors

Yamixa Delgado, Moraima Morales-Cruz, José Hernández-Román, Yashira Martínez, Kai Griebenow

Abstract

Cytochrome c (Cyt c) is an apoptosis-initiating protein when released into the cytoplasm of eukaryotic cells and therefore a possible cancer drug candidate. Although proteins have been increasingly important as pharmaceutical agents, their chemical and physical instability during production, storage, and delivery remains a problem. Chemical glycosylation has been devised as a method to increase protein stability and thus enhance their long-lasting bioavailability.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
Unknown 31 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 25%
Student > Master 5 16%
Student > Bachelor 2 6%
Student > Doctoral Student 2 6%
Librarian 2 6%
Other 8 25%
Unknown 5 16%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 8 25%
Agricultural and Biological Sciences 7 22%
Chemistry 4 13%
Engineering 2 6%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Other 6 19%
Unknown 4 13%