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TLR4 enhances histamine-mediated pruritus by potentiating TRPV1 activity

Overview of attention for article published in Molecular Brain, August 2014
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Title
TLR4 enhances histamine-mediated pruritus by potentiating TRPV1 activity
Published in
Molecular Brain, August 2014
DOI 10.1186/s13041-014-0059-9
Pubmed ID
Authors

Hyunjung Min, Hyunkyoung Lee, Hyoungsub Lim, Yong Ho Jang, Sung Jun Chung, C Justin Lee, Sung Joong Lee

Abstract

Recent studies have indicated that Toll-like receptor 4 (TLR4), a pathogen-recognition receptor that triggers inflammatory signals in innate immune cells, is also expressed on sensory neurons, implicating its putative role in sensory signal transmission. However, the possible function of sensory neuron TLR4 has not yet been formally addressed. In this regard, we investigated the role of TLR4 in itch signal transmission.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Korea, Republic of 1 2%
Serbia 1 2%
Unknown 49 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 29%
Researcher 8 16%
Student > Bachelor 7 14%
Student > Doctoral Student 4 8%
Other 3 6%
Other 5 10%
Unknown 9 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 27%
Medicine and Dentistry 8 16%
Biochemistry, Genetics and Molecular Biology 7 14%
Neuroscience 5 10%
Pharmacology, Toxicology and Pharmaceutical Science 3 6%
Other 5 10%
Unknown 9 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 August 2014.
All research outputs
#18,376,056
of 22,760,687 outputs
Outputs from Molecular Brain
#858
of 1,106 outputs
Outputs of similar age
#168,218
of 235,897 outputs
Outputs of similar age from Molecular Brain
#22
of 23 outputs
Altmetric has tracked 22,760,687 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,106 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 235,897 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.