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Tissue-resident stem cell activity: a view from the adult Drosophila gastrointestinal tract

Overview of attention for article published in Cell Communication and Signaling, September 2017
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  • Good Attention Score compared to outputs of the same age and source (70th percentile)

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3 X users

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40 Mendeley
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Title
Tissue-resident stem cell activity: a view from the adult Drosophila gastrointestinal tract
Published in
Cell Communication and Signaling, September 2017
DOI 10.1186/s12964-017-0184-z
Pubmed ID
Authors

Qiang Liu, Li Hua Jin

Abstract

The gastrointestinal tract serves as a fast-renewing model for unraveling the multifaceted molecular mechanisms underlying remarkably rapid cell renewal, which is exclusively fueled by a small number of long-lived stem cells and their progeny. Stem cell activity is the best-characterized aspect of mucosal homeostasis in mitotically active tissues, and the dysregulation of regenerative capacity is a hallmark of epithelial immune defects. This dysregulation is frequently associated with pathologies ranging from chronic enteritis to malignancies in humans. Application of the adult Drosophila gastrointestinal tract model in current and future studies to analyze the immuno-physiological aspects of epithelial defense strategies, including stem cell behavior and re-epithelialization, will be necessary to improve our general understanding of stem cell participation in epithelial turnover. In this review, which describes exciting observations obtained from the adult Drosophila gastrointestinal tract, we summarize a remarkable series of recent findings in the literature to decipher the molecular mechanisms through which stem cells respond to nonsterile environments.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 40 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 20%
Student > Master 7 18%
Student > Bachelor 7 18%
Researcher 5 13%
Lecturer 3 8%
Other 1 3%
Unknown 9 23%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 17 43%
Agricultural and Biological Sciences 6 15%
Chemistry 2 5%
Neuroscience 1 3%
Business, Management and Accounting 1 3%
Other 2 5%
Unknown 11 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 September 2017.
All research outputs
#14,223,188
of 23,577,654 outputs
Outputs from Cell Communication and Signaling
#332
of 1,070 outputs
Outputs of similar age
#168,548
of 319,391 outputs
Outputs of similar age from Cell Communication and Signaling
#3
of 10 outputs
Altmetric has tracked 23,577,654 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,070 research outputs from this source. They receive a mean Attention Score of 3.9. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 319,391 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 7 of them.