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Chebulagic acid from Terminalia chebula causes G1 arrest, inhibits NFκB and induces apoptosis in retinoblastoma cells

Overview of attention for article published in BMC Complementary Medicine and Therapies, August 2014
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Title
Chebulagic acid from Terminalia chebula causes G1 arrest, inhibits NFκB and induces apoptosis in retinoblastoma cells
Published in
BMC Complementary Medicine and Therapies, August 2014
DOI 10.1186/1472-6882-14-319
Pubmed ID
Authors

Naresh Kumar, Gangappa D, Geetika Gupta, Roy Karnati

Abstract

Plants are the valuable source of natural products with important medicinal properties. Most of the approved anti cancer drugs have a natural product origin or are natural products. Retinoblastoma is the most common ocular cancer of children. Although chemotherapy is the preferred mode of therapy, a successful treatment for retinoblastoma requires enucleation. Chebulagic acid (CA) from Terminalia chebula was shown to have anti-proliferative properties in the studies on cancerous cell lines. Due to anti cancer properties of CA and due to limitation in treatment options for retinoblastoma, the present study is undertaken to understand the role of CA on the proliferation of retinoblastoma cells.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 40 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 35%
Student > Master 5 13%
Student > Bachelor 4 10%
Researcher 3 8%
Professor 2 5%
Other 5 13%
Unknown 7 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 6 15%
Medicine and Dentistry 6 15%
Biochemistry, Genetics and Molecular Biology 5 13%
Immunology and Microbiology 4 10%
Pharmacology, Toxicology and Pharmaceutical Science 3 8%
Other 9 23%
Unknown 7 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 August 2014.
All research outputs
#15,304,580
of 22,761,738 outputs
Outputs from BMC Complementary Medicine and Therapies
#2,038
of 3,621 outputs
Outputs of similar age
#136,395
of 236,210 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#66
of 116 outputs
Altmetric has tracked 22,761,738 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,621 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.5. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 236,210 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 116 others from the same source and published within six weeks on either side of this one. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.