You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Precision genome engineering in lactic acid bacteria
|
|---|---|
| Published in |
Microbial Cell Factories, January 2014
|
| DOI | 10.1186/1475-2859-13-s1-s10 |
| Pubmed ID | |
| Authors |
Jan Peter van Pijkeren, Robert A Britton |
| Abstract |
Innovative new genome engineering technologies for manipulating chromosomes have appeared in the last decade. One of these technologies, recombination mediated genetic engineering (recombineering) allows for precision DNA engineering of chromosomes and plasmids in Escherichia coli. Single-stranded DNA recombineering (SSDR) allows for the generation of subtle mutations without the need for selection and without leaving behind any foreign DNA. In this review we discuss the application of SSDR technology in lactic acid bacteria, with an emphasis on key factors that were critical to move this technology from E. coli into Lactobacillus reuteri and Lactococcus lactis. We also provide a blueprint for how to proceed if one is attempting to establish SSDR technology in a lactic acid bacterium. The emergence of CRISPR-Cas technology in genome engineering and its potential application to enhancing SSDR in lactic acid bacteria is discussed. The ability to perform precision genome engineering in medically and industrially important lactic acid bacteria will allow for the genetic improvement of strains without compromising safety. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 40% |
| France | 1 | 20% |
| Netherlands | 1 | 20% |
| Unknown | 1 | 20% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 80% |
| Scientists | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 244 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Estonia | 2 | <1% |
| Belgium | 2 | <1% |
| Indonesia | 1 | <1% |
| Australia | 1 | <1% |
| Netherlands | 1 | <1% |
| Germany | 1 | <1% |
| Mexico | 1 | <1% |
| China | 1 | <1% |
| United States | 1 | <1% |
| Other | 0 | 0% |
| Unknown | 233 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 59 | 24% |
| Student > Ph. D. Student | 58 | 24% |
| Student > Master | 29 | 12% |
| Student > Bachelor | 24 | 10% |
| Other | 12 | 5% |
| Other | 43 | 18% |
| Unknown | 19 | 8% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 103 | 42% |
| Biochemistry, Genetics and Molecular Biology | 74 | 30% |
| Immunology and Microbiology | 11 | 5% |
| Engineering | 10 | 4% |
| Environmental Science | 4 | 2% |
| Other | 12 | 5% |
| Unknown | 30 | 12% |
Attention Score in Context
This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 January 2021.
All research outputs
#2,172,663
of 22,761,738 outputs
Outputs from Microbial Cell Factories
#63
of 1,595 outputs
Outputs of similar age
#26,726
of 305,296 outputs
Outputs of similar age from Microbial Cell Factories
#4
of 43 outputs
Altmetric has tracked 22,761,738 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,595 research outputs from this source. They receive a mean Attention Score of 4.4. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 305,296 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 43 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.