Title |
Comparison of an assumed versus measured leucocyte count in parasite density calculations in Papua New Guinean children with uncomplicated malaria
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Published in |
Malaria Journal, April 2014
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DOI | 10.1186/1475-2875-13-145 |
Pubmed ID | |
Authors |
Moses Laman, Brioni R Moore, John Benjamin, Nixon Padapu, Nandao Tarongka, Peter Siba, Inoni Betuela, Ivo Mueller, Leanne J Robinson, Timothy M E Davis |
Abstract |
The accuracy of the World Health Organization method of estimating malaria parasite density from thick blood smears by assuming a white blood cell (WBC) count of 8,000/μL has been questioned in several studies. Since epidemiological investigations, anti-malarial efficacy trials and routine laboratory reporting in Papua New Guinea (PNG) have all relied on this approach, its validity was assessed as part of a trial of artemisinin-based combination therapy, which included blood smear microscopy and automated measurement of leucocyte densities on Days 0, 3 and 7. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Kenya | 1 | 4% |
Unknown | 25 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 7 | 27% |
Student > Bachelor | 3 | 12% |
Researcher | 3 | 12% |
Other | 2 | 8% |
Student > Ph. D. Student | 2 | 8% |
Other | 5 | 19% |
Unknown | 4 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 10 | 38% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 8% |
Biochemistry, Genetics and Molecular Biology | 2 | 8% |
Immunology and Microbiology | 2 | 8% |
Nursing and Health Professions | 1 | 4% |
Other | 4 | 15% |
Unknown | 5 | 19% |