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X Demographics
Mendeley readers
| Title |
Q&A: How can advances in tissue clearing and optogenetics contribute to our understanding of normal and diseased biology?
|
|---|---|
| Published in |
BMC Biology, September 2017
|
| DOI | 10.1186/s12915-017-0421-3 |
| Pubmed ID | |
| Authors |
Alon Greenbaum, Min J. Jang, Collin Challis, Viviana Gradinaru |
| Abstract |
Mammalian organs comprise a variety of cells that interact with each other and have distinct biological roles. Access to evaluate and perturb intact biological systems at the cellular and molecular levels is essential to fully understand their functioning in normal and diseased conditions, yet technical limitations have constrained most research to small pieces of tissue. Tissue clearing and optogenetics can help overcome this hurdle: tissue clearing affords optical interrogation of whole organs at the molecular level, and optogenetics enables the scalable control and measurement of cellular activity with light. In this Q&A, we delineate recent advances and practical challenges associated with these two techniques when applied body-wide. |
X Demographics
The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 25% |
| United Kingdom | 2 | 25% |
| Unknown | 4 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 63% |
| Science communicators (journalists, bloggers, editors) | 2 | 25% |
| Scientists | 1 | 13% |
Mendeley readers
The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 48 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 10 | 21% |
| Student > Ph. D. Student | 9 | 19% |
| Student > Bachelor | 7 | 15% |
| Student > Doctoral Student | 4 | 8% |
| Student > Master | 3 | 6% |
| Other | 5 | 10% |
| Unknown | 10 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 12 | 25% |
| Biochemistry, Genetics and Molecular Biology | 6 | 13% |
| Agricultural and Biological Sciences | 5 | 10% |
| Engineering | 5 | 10% |
| Chemistry | 3 | 6% |
| Other | 5 | 10% |
| Unknown | 12 | 25% |