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Bioenergetic modulation with dichloroacetate reduces the growth of melanoma cells and potentiates their response to BRAFV600E inhibition

Overview of attention for article published in Journal of Translational Medicine, September 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (77th percentile)
  • Good Attention Score compared to outputs of the same age and source (79th percentile)

Mentioned by

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5 X users
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1 patent

Citations

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38 Dimensions

Readers on

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54 Mendeley
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Title
Bioenergetic modulation with dichloroacetate reduces the growth of melanoma cells and potentiates their response to BRAFV600E inhibition
Published in
Journal of Translational Medicine, September 2014
DOI 10.1186/s12967-014-0247-5
Pubmed ID
Authors

Cecilie Abildgaard, Christina Dahl, Astrid L Basse, Tao Ma, Per Guldberg

Abstract

Advances in melanoma treatment through targeted inhibition of oncogenic BRAF are limited owing to the development of acquired resistance. The involvement of BRAFV600E in metabolic reprogramming of melanoma cells provides a rationale for co-targeting metabolism as a therapeutic approach.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Denmark 1 2%
Canada 1 2%
Unknown 52 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 15 28%
Student > Ph. D. Student 14 26%
Student > Bachelor 7 13%
Student > Master 6 11%
Professor > Associate Professor 2 4%
Other 4 7%
Unknown 6 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 19 35%
Biochemistry, Genetics and Molecular Biology 12 22%
Medicine and Dentistry 6 11%
Mathematics 1 2%
Immunology and Microbiology 1 2%
Other 3 6%
Unknown 12 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 November 2020.
All research outputs
#5,440,940
of 22,763,032 outputs
Outputs from Journal of Translational Medicine
#835
of 3,980 outputs
Outputs of similar age
#52,813
of 237,864 outputs
Outputs of similar age from Journal of Translational Medicine
#16
of 78 outputs
Altmetric has tracked 22,763,032 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,980 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 237,864 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 78 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 79% of its contemporaries.