↓ Skip to main content

Capturing needles in haystacks: a comparison of B-cell receptor sequencing methods

Overview of attention for article published in BMC Immunology, August 2014
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#50 of 592)
  • High Attention Score compared to outputs of the same age (83rd percentile)
  • Good Attention Score compared to outputs of the same age and source (71st percentile)

Mentioned by

twitter
4 X users
patent
3 patents

Citations

dimensions_citation
46 Dimensions

Readers on

mendeley
158 Mendeley
citeulike
2 CiteULike
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Capturing needles in haystacks: a comparison of B-cell receptor sequencing methods
Published in
BMC Immunology, August 2014
DOI 10.1186/s12865-014-0029-0
Pubmed ID
Authors

Rachael JM Bashford-Rogers, Anne L Palser, Saad F Idris, Lisa Carter, Michael Epstein, Robin E Callard, Daniel C Douek, George S Vassiliou, George A Follows, Mike Hubank, Paul Kellam

Abstract

Deep-sequencing methods are rapidly developing in the field of B-cell receptor (BCR) and T-cell receptor (TCR) diversity. These promise to revolutionise our understanding of adaptive immune dynamics, identify novel antibodies, and allow monitoring of minimal residual disease. However, different methods for BCR and TCR enrichment and amplification have been proposed. Here we perform the first systematic comparison between different methods of enrichment, amplification and sequencing for generating BCR and TCR repertoires using large sample numbers.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 158 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 5 3%
United Kingdom 3 2%
Russia 3 2%
Germany 1 <1%
Unknown 146 92%

Demographic breakdown

Readers by professional status Count As %
Researcher 51 32%
Student > Ph. D. Student 35 22%
Student > Bachelor 10 6%
Student > Master 10 6%
Other 7 4%
Other 23 15%
Unknown 22 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 45 28%
Immunology and Microbiology 29 18%
Biochemistry, Genetics and Molecular Biology 28 18%
Medicine and Dentistry 15 9%
Engineering 5 3%
Other 9 6%
Unknown 27 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 April 2022.
All research outputs
#3,844,442
of 23,570,677 outputs
Outputs from BMC Immunology
#50
of 592 outputs
Outputs of similar age
#37,734
of 231,833 outputs
Outputs of similar age from BMC Immunology
#2
of 7 outputs
Altmetric has tracked 23,570,677 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 592 research outputs from this source. They receive a mean Attention Score of 3.8. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 231,833 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.