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Tolerability to romidepsin in patients with relapsed/refractory T-cell lymphoma

Overview of attention for article published in Biomarker Research, September 2014
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Title
Tolerability to romidepsin in patients with relapsed/refractory T-cell lymphoma
Published in
Biomarker Research, September 2014
DOI 10.1186/2050-7771-2-16
Pubmed ID
Authors

Francine Foss, Bertrand Coiffier, Steven Horwitz, Barbara Pro, H Miles Prince, Lubomir Sokol, Matthew Greenwood, Adam Lerner, Dolores Caballero, Eugeniusz Baran, Ellen Kim, Jean Nichols, Barbara Balser, Julie Wolfson, Sean Whittaker

Abstract

Histone deacetylase inhibitor romidepsin has demonstrated durable clinical responses and tolerability in patients with relapsed/refractory peripheral and cutaneous T-cell lymphoma (PTCL, CTCL). Selection of novel drug therapies for patients with relapsed/refractory aggressive lymphoma requires not only considerations regarding efficacy but also careful evaluation of toxicities as well as overall clinical benefit. The purpose of this analysis was to examine common adverse events (AEs) reported in pivotal trials of romidepsin in relapsed/refractory PTCL or CTCL and to more clearly define the overall AE profile in these populations.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 7%
Unknown 14 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 20%
Student > Master 3 20%
Student > Bachelor 2 13%
Other 1 7%
Student > Doctoral Student 1 7%
Other 1 7%
Unknown 4 27%
Readers by discipline Count As %
Medicine and Dentistry 4 27%
Pharmacology, Toxicology and Pharmaceutical Science 3 20%
Agricultural and Biological Sciences 2 13%
Biochemistry, Genetics and Molecular Biology 1 7%
Economics, Econometrics and Finance 1 7%
Other 1 7%
Unknown 3 20%