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Interactions of unconjugated bilirubin with vesicles, cyclodextrins and micelles: New modeling and the role of high pKa values

Overview of attention for article published in BMC Molecular and Cell Biology, March 2010
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Title
Interactions of unconjugated bilirubin with vesicles, cyclodextrins and micelles: New modeling and the role of high pKa values
Published in
BMC Molecular and Cell Biology, March 2010
DOI 10.1186/1471-2091-11-16
Pubmed ID
Authors

Pasupati Mukerjee, J Donald Ostrow

Abstract

Unconjugated bilirubin (UCB) is an unstable substance with very low aqueous solubility. Its aqueous pKa values affect many of its interactions, particularly their pH-dependence. A companion paper shows that only our prior solvent partition studies, leading to pKa values of 8.12 and 8.44, met all essential requirements for valid pKa determinations. Other published values, generally lower, some below 5.0, were shown to be invalid. The present work was designed to derive suitable models for interpreting published data on the pH-dependent binding of UCB with four agents, mentioned below, chosen because they are not, themselves, sensitive to changes in the pH range 4-10, and the data, mainly spectrometric, were of reasonable quality.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Czechia 1 5%
Peru 1 5%
Argentina 1 5%
Unknown 19 86%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 32%
Researcher 4 18%
Student > Postgraduate 2 9%
Student > Master 2 9%
Student > Bachelor 1 5%
Other 1 5%
Unknown 5 23%
Readers by discipline Count As %
Chemistry 5 23%
Biochemistry, Genetics and Molecular Biology 3 14%
Agricultural and Biological Sciences 3 14%
Medicine and Dentistry 2 9%
Psychology 1 5%
Other 4 18%
Unknown 4 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 September 2014.
All research outputs
#20,657,128
of 25,374,917 outputs
Outputs from BMC Molecular and Cell Biology
#935
of 1,233 outputs
Outputs of similar age
#94,298
of 103,741 outputs
Outputs of similar age from BMC Molecular and Cell Biology
#21
of 21 outputs
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So far Altmetric has tracked 1,233 research outputs from this source. They receive a mean Attention Score of 4.0. This one is in the 14th percentile – i.e., 14% of its peers scored the same or lower than it.
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We're also able to compare this research output to 21 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.