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Calcineurin and glial signaling: neuroinflammation and beyond

Overview of attention for article published in Journal of Neuroinflammation, September 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (87th percentile)

Mentioned by

blogs
1 blog
twitter
1 tweeter

Citations

dimensions_citation
65 Dimensions

Readers on

mendeley
76 Mendeley
citeulike
1 CiteULike
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Title
Calcineurin and glial signaling: neuroinflammation and beyond
Published in
Journal of Neuroinflammation, September 2014
DOI 10.1186/s12974-014-0158-7
Pubmed ID
Authors

Jennifer L Furman, Christopher M Norris

Abstract

Similar to peripheral immune/inflammatory cells, neuroglial cells appear to rely on calcineurin (CN) signaling pathways to regulate cytokine production and cellular activation. Several studies suggest that harmful immune/inflammatory responses may be the most impactful consequence of aberrant CN activity in glial cells. However, newly identified roles for CN in glutamate uptake, gap junction regulation, Ca2+ dyshomeostasis, and amyloid production suggest that CN¿s influence in glia may extend well beyond neuroinflammation. The following review will discuss the various actions of CN in glial cells, with particular emphasis on astrocytes, and consider the implications for neurologic dysfunction arising with aging, injury, and/or neurodegenerative disease.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 76 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Denmark 1 1%
Unknown 75 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 22%
Researcher 10 13%
Student > Master 9 12%
Student > Bachelor 8 11%
Professor 4 5%
Other 13 17%
Unknown 15 20%
Readers by discipline Count As %
Neuroscience 20 26%
Agricultural and Biological Sciences 18 24%
Biochemistry, Genetics and Molecular Biology 7 9%
Medicine and Dentistry 4 5%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Other 6 8%
Unknown 19 25%

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 October 2014.
All research outputs
#2,281,603
of 18,635,251 outputs
Outputs from Journal of Neuroinflammation
#348
of 2,213 outputs
Outputs of similar age
#27,501
of 211,870 outputs
Outputs of similar age from Journal of Neuroinflammation
#1
of 4 outputs
Altmetric has tracked 18,635,251 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,213 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 211,870 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them