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Calcineurin and glial signaling: neuroinflammation and beyond

Overview of attention for article published in Journal of Neuroinflammation, September 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • High Attention Score compared to outputs of the same age and source (93rd percentile)

Mentioned by

blogs
1 blog
twitter
1 X user

Citations

dimensions_citation
86 Dimensions

Readers on

mendeley
85 Mendeley
citeulike
1 CiteULike
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Title
Calcineurin and glial signaling: neuroinflammation and beyond
Published in
Journal of Neuroinflammation, September 2014
DOI 10.1186/s12974-014-0158-7
Pubmed ID
Authors

Jennifer L Furman, Christopher M Norris

Abstract

Similar to peripheral immune/inflammatory cells, neuroglial cells appear to rely on calcineurin (CN) signaling pathways to regulate cytokine production and cellular activation. Several studies suggest that harmful immune/inflammatory responses may be the most impactful consequence of aberrant CN activity in glial cells. However, newly identified roles for CN in glutamate uptake, gap junction regulation, Ca2+ dyshomeostasis, and amyloid production suggest that CN¿s influence in glia may extend well beyond neuroinflammation. The following review will discuss the various actions of CN in glial cells, with particular emphasis on astrocytes, and consider the implications for neurologic dysfunction arising with aging, injury, and/or neurodegenerative disease.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 85 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Denmark 1 1%
Unknown 84 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 20%
Researcher 10 12%
Student > Master 10 12%
Student > Bachelor 8 9%
Professor 4 5%
Other 12 14%
Unknown 24 28%
Readers by discipline Count As %
Neuroscience 20 24%
Agricultural and Biological Sciences 18 21%
Biochemistry, Genetics and Molecular Biology 7 8%
Medicine and Dentistry 4 5%
Pharmacology, Toxicology and Pharmaceutical Science 2 2%
Other 5 6%
Unknown 29 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 October 2014.
All research outputs
#2,870,587
of 22,763,032 outputs
Outputs from Journal of Neuroinflammation
#473
of 2,621 outputs
Outputs of similar age
#31,768
of 238,994 outputs
Outputs of similar age from Journal of Neuroinflammation
#2
of 31 outputs
Altmetric has tracked 22,763,032 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,621 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 238,994 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.