Title |
MicroRNA-34 family expression in bovine gametes and preimplantation embryos
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Published in |
Reproductive Biology and Endocrinology, September 2014
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DOI | 10.1186/1477-7827-12-85 |
Pubmed ID | |
Authors |
Allison Tscherner, Graham Gilchrist, Natasha Smith, Patrick Blondin, Daniel Gillis, Jonathan LaMarre |
Abstract |
Oocyte fertilization and successful embryo implantation are key events marking the onset of pregnancy. In sexually reproducing organisms, embryogenesis begins with the fusion of two haploid gametes, each of which has undergone progressive stages of maturation. In the final stages of oocyte maturation, minimal transcriptional activity is present and regulation of gene expression occurs primarily at the post-transcriptional level. MicroRNAs (miRNA) are potent effectors of post-transcriptional gene silencing and recent evidence demonstrates that the miR-34 family of miRNA are involved in both spermatogenesis and early events of embryogenesis. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 33% |
United Kingdom | 2 | 33% |
France | 1 | 17% |
Unknown | 1 | 17% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 50% |
Scientists | 3 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | 1% |
Greece | 1 | 1% |
Unknown | 65 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 12 | 18% |
Student > Ph. D. Student | 11 | 16% |
Student > Master | 9 | 13% |
Student > Bachelor | 6 | 9% |
Student > Postgraduate | 6 | 9% |
Other | 9 | 13% |
Unknown | 14 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 20 | 30% |
Biochemistry, Genetics and Molecular Biology | 13 | 19% |
Medicine and Dentistry | 6 | 9% |
Veterinary Science and Veterinary Medicine | 4 | 6% |
Engineering | 2 | 3% |
Other | 8 | 12% |
Unknown | 14 | 21% |