↓ Skip to main content

The role of a lens survival pathway including sox2 and αA-crystallin in the evolution of cavefish eye degeneration

Overview of attention for article published in EvoDevo, August 2014
Altmetric Badge

About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (53rd percentile)

Mentioned by

twitter
4 tweeters

Citations

dimensions_citation
40 Dimensions

Readers on

mendeley
39 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
The role of a lens survival pathway including sox2 and αA-crystallin in the evolution of cavefish eye degeneration
Published in
EvoDevo, August 2014
DOI 10.1186/2041-9139-5-28
Pubmed ID
Authors

Li Ma, Amy Parkhurst, William R Jeffery

Abstract

The teleost Astyanax mexicanus is a single species consisting of eyed surface-dwelling (surface fish) and blind cave-dwelling (cavefish) morphs. Cavefish eyes are lost through apoptosis of the lens, which in turn promotes the degeneration of other optic tissues. The αA-crystallin (αA-crys) gene is strongly downregulated in the cavefish lens and is located in a genomic region (QTL) responsible for eye loss. Therefore, αA-crys has been proposed as a candidate for regulating cavefish eye degeneration. The purpose of this study was to determine the mechanism of αA-crys downregulation and its role in cavefish eye degeneration.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 5%
Unknown 37 95%

Demographic breakdown

Readers by professional status Count As %
Student > Master 9 23%
Student > Ph. D. Student 8 21%
Researcher 6 15%
Professor > Associate Professor 4 10%
Professor 2 5%
Other 6 15%
Unknown 4 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 18 46%
Biochemistry, Genetics and Molecular Biology 8 21%
Neuroscience 2 5%
Nursing and Health Professions 1 3%
Psychology 1 3%
Other 3 8%
Unknown 6 15%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 January 2021.
All research outputs
#11,749,869
of 20,133,627 outputs
Outputs from EvoDevo
#208
of 302 outputs
Outputs of similar age
#97,410
of 214,690 outputs
Outputs of similar age from EvoDevo
#1
of 1 outputs
Altmetric has tracked 20,133,627 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 302 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.5. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 214,690 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them