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Epigenetic Regulation of Spinal Cord Gene Expression Controls Opioid-Induced Hyperalgesia

Overview of attention for article published in Molecular Pain, January 2014
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Title
Epigenetic Regulation of Spinal Cord Gene Expression Controls Opioid-Induced Hyperalgesia
Published in
Molecular Pain, January 2014
DOI 10.1186/1744-8069-10-59
Pubmed ID
Authors

De-Yong Liang, Yuan Sun, Xiao-You Shi, Peyman Sahbaie, J David Clark

Abstract

The long term use of opioids for the treatment of pain leads to a group of maladaptations which includes opioid-induced hyperalgesia (OIH). OIH typically resolves within few days after cessation of morphine treatment in mice but is prolonged for weeks if histone deacetylase (HDAC) activity is inhibited during opioid treatment. The present work seeks to identify gene targets supporting the epigenetic effects responsible for OIH prolongation.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 44 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 30%
Researcher 7 16%
Student > Doctoral Student 6 14%
Student > Master 5 11%
Student > Bachelor 4 9%
Other 2 5%
Unknown 7 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 25%
Neuroscience 10 23%
Medicine and Dentistry 6 14%
Psychology 3 7%
Immunology and Microbiology 2 5%
Other 4 9%
Unknown 8 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 September 2014.
All research outputs
#20,656,820
of 25,374,647 outputs
Outputs from Molecular Pain
#477
of 669 outputs
Outputs of similar age
#243,193
of 319,281 outputs
Outputs of similar age from Molecular Pain
#35
of 58 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 669 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one is in the 11th percentile – i.e., 11% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 319,281 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.