Title |
Bioinformatic analysis of beta carbonic anhydrase sequences from protozoans and metazoans
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Published in |
Parasites & Vectors, January 2014
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DOI | 10.1186/1756-3305-7-38 |
Pubmed ID | |
Authors |
Reza Zolfaghari Emameh, Harlan Barker, Martti E E Tolvanen, Csaba Ortutay, Seppo Parkkila |
Abstract |
Despite the high prevalence of parasitic infections, and their impact on global health and economy, the number of drugs available to treat them is extremely limited. As a result, the potential consequences of large-scale resistance to any existing drugs are a major concern. A number of recent investigations have focused on the effects of potential chemical inhibitors on bacterial and fungal carbonic anhydrases. Among the five classes of carbonic anhydrases (alpha, beta, gamma, delta and zeta), beta carbonic anhydrases have been reported in most species of bacteria, yeasts, algae, plants, and particular invertebrates (nematodes and insects). To date, there has been a lack of knowledge on the expression and molecular structure of beta carbonic anhydrases in metazoan (nematodes and arthropods) and protozoan species. |
X Demographics
Geographical breakdown
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Finland | 1 | 2% |
Unknown | 47 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 13 | 27% |
Other | 6 | 13% |
Student > Postgraduate | 5 | 10% |
Student > Master | 4 | 8% |
Researcher | 3 | 6% |
Other | 7 | 15% |
Unknown | 10 | 21% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 15 | 31% |
Biochemistry, Genetics and Molecular Biology | 11 | 23% |
Medicine and Dentistry | 3 | 6% |
Computer Science | 3 | 6% |
Nursing and Health Professions | 1 | 2% |
Other | 3 | 6% |
Unknown | 12 | 25% |