Title |
White matter lesion filling improves the accuracy of cortical thickness measurements in multiple sclerosis patients: a longitudinal study
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Published in |
BMC Neuroscience, September 2014
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DOI | 10.1186/1471-2202-15-106 |
Pubmed ID | |
Authors |
Stefano Magon, Laura Gaetano, M Mallar Chakravarty, Jason P Lerch, Yvonne Naegelin, Christoph Stippich, Ludwig Kappos, Ernst-Wilhelm Radue, Till Sprenger |
Abstract |
Previous studies have demonstrated that white matter (WM) lesions bias automated brain tissue classifications and cerebral volume measurements. However, filling WM lesions using the intensity of neighbouring normal-appearing WM has been shown to increase the accuracy of automated volume measurements in the brain. In the present study, we investigate the influence of WM lesions on cortical thickness (CTh) measures and assessed the impact of lesion filling on both cross-sectional/longitudinal and global/regional measurements of CTh in multiple sclerosis (MS) patients. |
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Unknown | 4 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 4 | 100% |
Mendeley readers
Geographical breakdown
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Canada | 2 | 3% |
Italy | 1 | 1% |
Brazil | 1 | 1% |
Unknown | 69 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 19 | 26% |
Student > Master | 12 | 16% |
Researcher | 11 | 15% |
Other | 5 | 7% |
Student > Postgraduate | 5 | 7% |
Other | 12 | 16% |
Unknown | 9 | 12% |
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Neuroscience | 14 | 19% |
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Agricultural and Biological Sciences | 6 | 8% |
Psychology | 6 | 8% |
Other | 6 | 8% |
Unknown | 17 | 23% |