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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Endothelial cell metabolism: parallels and divergences with cancer cell metabolism
|
|---|---|
| Published in |
Cancer & Metabolism, September 2014
|
| DOI | 10.1186/2049-3002-2-19 |
| Pubmed ID | |
| Authors |
Dries Verdegem, Stijn Moens, Peter Stapor, Peter Carmeliet |
| Abstract |
The stromal vasculature in tumors is a vital conduit of nutrients and oxygen for cancer cells. To date, the vast majority of studies have focused on unraveling the genetic basis of vessel sprouting (also termed angiogenesis). In contrast to the widely studied changes in cancer cell metabolism, insight in the metabolic regulation of angiogenesis is only just emerging. These studies show that metabolic pathways in endothelial cells (ECs) importantly regulate angiogenesis in conjunction with genetic signals. In this review, we will highlight these emerging insights in EC metabolism and discuss them in perspective of cancer cell metabolism. While it is generally assumed that cancer cells have unique metabolic adaptations, not shared by healthy non-transformed cells, we will discuss parallels and highlight differences between endothelial and cancer cell metabolism and consider possible novel therapeutic opportunities arising from targeting both cancer and endothelial cells. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 138 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Finland | 1 | <1% |
| Russia | 1 | <1% |
| Italy | 1 | <1% |
| Canada | 1 | <1% |
| Unknown | 134 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 33 | 24% |
| Researcher | 21 | 15% |
| Student > Master | 13 | 9% |
| Student > Bachelor | 12 | 9% |
| Student > Postgraduate | 7 | 5% |
| Other | 27 | 20% |
| Unknown | 25 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 30 | 22% |
| Agricultural and Biological Sciences | 28 | 20% |
| Medicine and Dentistry | 22 | 16% |
| Engineering | 7 | 5% |
| Chemistry | 6 | 4% |
| Other | 15 | 11% |
| Unknown | 30 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 October 2022.
All research outputs
#14,408,783
of 23,543,207 outputs
Outputs from Cancer & Metabolism
#111
of 209 outputs
Outputs of similar age
#126,101
of 248,021 outputs
Outputs of similar age from Cancer & Metabolism
#4
of 6 outputs
Altmetric has tracked 23,543,207 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 209 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.9. This one is in the 42nd percentile – i.e., 42% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 248,021 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.