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Tryptophan depletion in chronic fatigue syndrome, a pilot cross-over study

Overview of attention for article published in BMC Research Notes, September 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (94th percentile)
  • High Attention Score compared to outputs of the same age and source (95th percentile)

Mentioned by

news
2 news outlets
blogs
1 blog
twitter
10 X users
facebook
6 Facebook pages

Citations

dimensions_citation
11 Dimensions

Readers on

mendeley
62 Mendeley
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Title
Tryptophan depletion in chronic fatigue syndrome, a pilot cross-over study
Published in
BMC Research Notes, September 2014
DOI 10.1186/1756-0500-7-650
Pubmed ID
Authors

Gerard KH The, Robbert J Verkes, Durk Fekkes, Gijs Bleijenberg, Jos WM van der Meer, Jan K Buitelaar

Abstract

Chronic fatigue syndrome (CFS) is still an enigmatic disorder. CFS can be regarded as a complex disorder with tremendous impact on lives of CFS-patients. Full recovery without treatment is rare. A somatic explanation for the fatigue is lacking. There is clinical and experimental evidence implicating enhanced serotonergic neurotransmission in CFS. Genetic studies and imaging studies support the hypothesis of upregulated serotonin system in CFS. In line with the hypothesis of an increased serotonergic state in CFS, we performed a randomised clinical trial investigated the effect of 5-HT3 receptor antagonism in CFS. No benefit was found of the 5-HT3 receptor antagonist ondansetron compared to placebo.To further investigate the involvement of serotonin in CFS we performed a placebo controlled cross over pilot study investigating the effect of Acute Tryptophan Depletion.

X Demographics

X Demographics

The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 62 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 62 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 16%
Researcher 9 15%
Student > Master 8 13%
Student > Bachelor 8 13%
Student > Doctoral Student 5 8%
Other 13 21%
Unknown 9 15%
Readers by discipline Count As %
Psychology 15 24%
Medicine and Dentistry 9 15%
Agricultural and Biological Sciences 6 10%
Biochemistry, Genetics and Molecular Biology 5 8%
Nursing and Health Professions 4 6%
Other 10 16%
Unknown 13 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 30. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 April 2024.
All research outputs
#1,321,716
of 25,753,031 outputs
Outputs from BMC Research Notes
#144
of 4,525 outputs
Outputs of similar age
#13,079
of 247,136 outputs
Outputs of similar age from BMC Research Notes
#7
of 157 outputs
Altmetric has tracked 25,753,031 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,525 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 247,136 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 157 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.