Title |
Protocol for a systematic review and individual patient data meta-analysis of benefit of so-called lung-protective ventilation settings in patients under general anesthesia for surgery
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Published in |
Systematic Reviews, January 2014
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DOI | 10.1186/2046-4053-3-2 |
Pubmed ID | |
Authors |
Ary Serpa Neto, Sabrine NT Hemmes, Marcelo Gama de Abreu, Paolo Pelosi, Marcus J Schultz |
Abstract |
Almost all patients under general anesthesia for surgery need mechanical ventilation. The harmful effects of short-term intra-operative ventilation on pulmonary integrity are increasingly recognized. Recent investigations suggest protection against so-called ventilation-associated lung injury with the use of lower tidal volumes and/or the use of higher levels of positive end-expiratory pressure (PEEP). This review and meta-analysis will evaluate the effects of these protective measures on pulmonary and extra-pulmonary complications, and try to discriminate the effects of lower tidal volumes from those of higher levels of PEEP. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 2 | 4% |
Israel | 1 | 2% |
Unknown | 50 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 12 | 23% |
Student > Postgraduate | 8 | 15% |
Other | 7 | 13% |
Student > Master | 6 | 11% |
Student > Ph. D. Student | 4 | 8% |
Other | 9 | 17% |
Unknown | 7 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 40 | 75% |
Nursing and Health Professions | 2 | 4% |
Computer Science | 1 | 2% |
Biochemistry, Genetics and Molecular Biology | 1 | 2% |
Unknown | 9 | 17% |