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Maternal caffeine intake during pregnancy is associated with risk of low birth weight: a systematic review and dose-response meta-analysis

Overview of attention for article published in BMC Medicine, September 2014
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Mentioned by

news
17 news outlets
blogs
3 blogs
policy
1 policy source
twitter
32 tweeters
facebook
5 Facebook pages
wikipedia
3 Wikipedia pages
googleplus
1 Google+ user
video
2 video uploaders

Citations

dimensions_citation
75 Dimensions

Readers on

mendeley
187 Mendeley
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Title
Maternal caffeine intake during pregnancy is associated with risk of low birth weight: a systematic review and dose-response meta-analysis
Published in
BMC Medicine, September 2014
DOI 10.1186/s12916-014-0174-6
Pubmed ID
Authors

Ling-Wei Chen, Yi Wu, Nithya Neelakantan, Mary Foong-Fong Chong, An Pan, Rob M van Dam

Abstract

BackgroundConsiderable controversy exists regarding the relation between maternal caffeine intake during pregnancy and risk of low birth weight (birth weight <2,500 g). We aim to assess this association using a systematic review and dose¿response meta-analysis of prospective studies.MethodsPotential articles were identified by searching MEDLINE and SCOPUS databases through 17 July 2013. Two authors independently extracted information on study design, participant characteristics and estimates of associations. Random-effects models were used to derive the summary relative risks (RRs) and corresponding 95% confidence intervals (CIs). Dose¿response relationships were assessed using generalized least-squares trend estimation.ResultsIn our meta-analysis, we included 13 prospective studies: 9 with low birth weight as a binary outcome variable (90,747 participants and 6,303 cases) and 6 with birth weight as a continuous outcome variable (10,015 participants; 2 studies reported both types of outcomes). Compared with the reference category with no or very low caffeine intake, the RR (95% CI) of low birth weight was 1.13 (1.06 to 1.21; I 2 0.0%) for low intake (50 to 149 mg/day), 1.38 (1.18 to 1.62; I 2 31.9%) for moderate intake (150 to 349 mg/day), and 1.60 (1.24 to 2.08; I 2 65.8%) for high intake (¿350 mg/day). In the dose¿response analysis, each 100-mg/day increment in maternal caffeine intake (around one cup of coffee) was associated with 13% (RR 1.13, 1.06 to 1.21) higher risk of low birth weight. The association persisted in strata defined according to various study characteristics. Moderate (¿33 g, 95% CI ¿63 to ¿4; I 2 0.3%) and high (¿69 g, 95% CI ¿102 to ¿35; I 2 0.0%) caffeine intakes were also associated with a significantly lower birth weight as compared with the reference category.ConclusionsHigher maternal caffeine intake during pregnancy was associated with a higher risk of delivering low birth weight infants. These findings support recommendations to restrict caffeine intake during pregnancy to low levels.

Twitter Demographics

The data shown below were collected from the profiles of 32 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 187 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Ethiopia 1 <1%
Australia 1 <1%
Brazil 1 <1%
Slovenia 1 <1%
Mexico 1 <1%
Unknown 182 97%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 65 35%
Student > Master 32 17%
Researcher 16 9%
Student > Ph. D. Student 14 7%
Other 10 5%
Other 20 11%
Unknown 30 16%
Readers by discipline Count As %
Medicine and Dentistry 74 40%
Agricultural and Biological Sciences 17 9%
Nursing and Health Professions 16 9%
Biochemistry, Genetics and Molecular Biology 10 5%
Psychology 5 3%
Other 29 16%
Unknown 36 19%

Attention Score in Context

This research output has an Altmetric Attention Score of 192. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 July 2021.
All research outputs
#125,916
of 19,146,896 outputs
Outputs from BMC Medicine
#111
of 2,863 outputs
Outputs of similar age
#1,401
of 219,942 outputs
Outputs of similar age from BMC Medicine
#1
of 12 outputs
Altmetric has tracked 19,146,896 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,863 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 39.4. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 219,942 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.