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X Demographics
Mendeley readers
Attention Score in Context
| Title |
A randomized controlled double blind trial comparing the effects of the prophylactic antibiotic, Cefazolin, administered at caesarean delivery at two different timings (before skin incision and after cord clamping) on both the mother and newborn
|
|---|---|
| Published in |
BMC Pregnancy and Childbirth, October 2017
|
| DOI | 10.1186/s12884-017-1526-y |
| Pubmed ID | |
| Authors |
Chinta Annie Jyothirmayi, Ajay Halder, Bijesh Yadav, Santosh Thomas Samuel, Anil Kuruvilla, Ruby Jose |
| Abstract |
Caesarean delivery (CD) increases the risk of postpartum infection by 5 to 20 fold. Prevention of surgical site infection (SSI) is the goal of antibiotic prophylaxis. This study was carried out to assess the optimum timing for prophylactic antibiotic administration and to assess the amount of the antibiotic crossing the placental barrier. Eligible mothers were recruited, after informed consent, once the decision for CD was made. Each mother received two injections, one prior to skin incision and one after cord clamping, (one being the study drug Cefazolin, and the other, a placebo) based on the randomization code. Demographic, maternal and neonatal monitoring data until discharge from hospital, and at the 6 weeks postpartum visit were collected. Levels of the prophylactic antibiotic were measured from the cord blood in every 8th neonate. The objective of the study was to compare the effects of the prophylactic antibiotic, intravenous Cefazolin 1 g, administered at Caesarean delivery (CD) at two different timings (before skin incision and after cord clamping) on both the mother and newborn. The secondary outcomes that were followed up were the number of maternal and neonatal readmissions. An appropriate test for significance, Fisher's exact test was used to find the association between risk variables and outcome. The total numbers of mothers enrolled were 1106, of whom 553 mothers received antibiotic prior to skin incision (pre-incision) and 543 mothers received antibiotic after cord clamping (post-incision). The pre-incision group had significantly less febrile illness (RR = 0.48, 95% CI: 0.29 - 0.80) and SSI (RR = 0.14, 95% CI: 0.04 - 0.53) when compared with the post- incision group. The post-incision group significantly had >7 days hospital stay when compared to the 4-7 days stay of the pre-incision group (p = 0.005).There were no differences in any of the neonatal outcomes. The quantity of the antibiotic in the cord blood was only 2-3%. Pre incision prophylactic antibiotic protected the mother from SSI and febrile illness and decreased the hospital stay significantly. The Clinical Trials Registry India (CTRI) was [ CTRI/2016/03/006710 dated, 04/03/2016]. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Ireland | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 132 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 132 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 20 | 15% |
| Researcher | 13 | 10% |
| Student > Bachelor | 11 | 8% |
| Student > Ph. D. Student | 8 | 6% |
| Professor | 6 | 5% |
| Other | 21 | 16% |
| Unknown | 53 | 40% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 30 | 23% |
| Nursing and Health Professions | 14 | 11% |
| Pharmacology, Toxicology and Pharmaceutical Science | 9 | 7% |
| Social Sciences | 7 | 5% |
| Psychology | 5 | 4% |
| Other | 12 | 9% |
| Unknown | 55 | 42% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 January 2020.
All research outputs
#7,029,007
of 23,005,189 outputs
Outputs from BMC Pregnancy and Childbirth
#1,947
of 4,234 outputs
Outputs of similar age
#113,618
of 323,064 outputs
Outputs of similar age from BMC Pregnancy and Childbirth
#54
of 97 outputs
Altmetric has tracked 23,005,189 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 4,234 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.9. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 323,064 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.
We're also able to compare this research output to 97 others from the same source and published within six weeks on either side of this one. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.