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A multicentre non-blinded randomised controlled trial to assess the impact of regular early specialist symptom control treatment on quality of life in malignant mesothelioma (RESPECT-MESO): study…

Overview of attention for article published in Trials, September 2014
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Title
A multicentre non-blinded randomised controlled trial to assess the impact of regular early specialist symptom control treatment on quality of life in malignant mesothelioma (RESPECT-MESO): study protocol for a randomised controlled trial
Published in
Trials, September 2014
DOI 10.1186/1745-6215-15-367
Pubmed ID
Authors

Samal Gunatilake, Fraser JH Brims, Carole Fogg, Iain Lawrie, Nick Maskell, Karen Forbes, Najib Rahman, Steve Morris, Reuben Ogollah, Stephen Gerry, Mick Peake, Liz Darlison, Anoop J Chauhan

Abstract

Malignant pleural mesothelioma is an incurable cancer caused by exposure to asbestos. The United Kingdom has the highest death rate from mesothelioma in the world and this figure is increasing. Median survival is 8 to 12 months, and most patients have symptoms at diagnosis. The fittest patients may be offered chemotherapy with palliative intent. For patients not fit for systemic anticancer treatment, best supportive care remains the mainstay of management. A study from the United States examining advanced lung cancer showed that early specialist palliative care input improved patient health related quality of life and depression symptoms 12 weeks after diagnosis. While mesothelioma and advanced lung cancer share many symptoms and have a poor prognosis, oncology and palliative care services in the United Kingdom, and many other countries, vary considerably compared to the United States. The aim of this trial is to assess whether regular early symptom control treatment provided by palliative care specialists can improve health related quality of life in patients newly diagnosed with mesothelioma.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 135 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 <1%
Unknown 134 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 22 16%
Researcher 17 13%
Student > Ph. D. Student 12 9%
Student > Bachelor 12 9%
Student > Postgraduate 7 5%
Other 21 16%
Unknown 44 33%
Readers by discipline Count As %
Medicine and Dentistry 29 21%
Nursing and Health Professions 21 16%
Psychology 8 6%
Pharmacology, Toxicology and Pharmaceutical Science 5 4%
Social Sciences 4 3%
Other 17 13%
Unknown 51 38%