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Mendeley readers
Title |
Extravasation into brain and subsequent spread beyond the ischemic core of a magnetic resonance contrast agent following a step-down infusion protocol in acute cerebral ischemia
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Published in |
Fluids and Barriers of the CNS, September 2014
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DOI | 10.1186/2045-8118-11-21 |
Pubmed ID | |
Authors |
Tavarekere N Nagaraja, Kelly A Keenan, Madhava P Aryal, James R Ewing, Saarang Gopinath, Varun S Nadig, Sukruth Shashikumar, Robert A Knight |
Abstract |
Limiting expansion of the ischemic core lesion by reinstating blood flow and protecting the penumbral cells is a priority in acute stroke treatment. However, at present, methods are not available for effective drug delivery to the ischemic penumbra. To address these issues this study compared the extravasation and subsequent interstitial spread of a magnetic resonance contrast agent (MRCA) beyond the ischemic core into the surrounding brain in a rat model of ischemia-reperfusion for bolus injection and step-down infusion (SDI) protocols. |
Mendeley readers
The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 24 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 7 | 29% |
Student > Postgraduate | 4 | 17% |
Student > Master | 3 | 13% |
Student > Ph. D. Student | 3 | 13% |
Other | 1 | 4% |
Other | 3 | 13% |
Unknown | 3 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 9 | 38% |
Neuroscience | 4 | 17% |
Agricultural and Biological Sciences | 3 | 13% |
Biochemistry, Genetics and Molecular Biology | 2 | 8% |
Social Sciences | 2 | 8% |
Other | 2 | 8% |
Unknown | 2 | 8% |